AI Article Synopsis
- VIM, IMP, and NDM are types of metallo-β-lactamases (MBLs) found globally, which can make bacteria resistant to antibiotics like carbapenems.
- SPM-1, identified in Brazil in 2002, was recently discovered in Chile within a Pseudomonas aeruginosa strain resistant to important antibiotics.
- The patient with SPM-1 had previously undergone an angioplasty in Brazil, prompting healthcare facilities to begin routine screening for SPM-1 in similar bacterial cultures.
Article Abstract
VIM, IMP, and NDM carbapenemases are metallo-β-lactamases (MBLs) that are widely distributed throughout the world. SPM-1 (Sao Paulo metallo-β-lactamase) is an MBL that was described in Pseudomonas aeruginosa in Sao Paulo (Brazil) in 2002. We report for the first time the presence of SPM-1 in Chile, in an isolate of P aeruginosa resistant to meropenem and imipenem, detected in a carbapenemase surveillance rectal swab culture, in a patient admitted to our institution. The sequence of the PCR product was 100% identical to the sequence of SPM-1 reported in Brazil. The patient had a history of an angioplasty performed in Brazil in 2004-2005. As a consequence of this finding, the detection of SPM by PCR will be incorporated into the routine screening for carbapenemases in P aeruginosa.
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| http://dx.doi.org/10.4067/s0716-10182021000500724 | DOI Listing |
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