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[Vitamin D deficiency/insufficiency on healthy infants receiving standard supplementation]. | LitMetric

AI Article Synopsis

  • Vitamin D is crucial for calcium and phosphorus metabolism, and a deficiency can lead to conditions like rickets; Chilean newborns receive daily VD supplementation for their first year.
  • A study aimed to assess plasma VD levels in healthy infants receiving this supplementation and explored the relationship between VD levels, seasonality, and nutritional status.
  • Results showed that 40% of the studied infants had VD deficiency, with lower levels linked to winter-spring seasons and infants at risk of malnutrition.

Article Abstract

Unlabelled: Vitamin D (VD) is essential for calcium and phosphorus metabolism. Its deficiency can cause rickets. In Chile, newborns receive 400UI/day supplementation from the first day of age until the first year.

Objective: To describe the VD plasma levels in healthy infants who received supplementation and secondarily to correlate this with seasonality and nutritional status.

Subjects And Method: Cross sectional study. Infants on exclusive or mixed breastfeeding, with monthly pediatric checkups recei ving 400 UI VD supplementation were evaluated, measuring VD plasma levels at 6 months of age, weight, and length, and their nutritional status was classified according to the WHO growth referen ces (weight/age and weight/length). The VD cut-off concentration values were < 20 ng/ml, 21- 29 ng/ ml, and ≥ 30 ng/ml considered as deficiency, insufficiency, and sufficiency, respectively.

Results: 40 infants were studied, 40% had insufficient levels and 40% presented deficiency. Season and nutritio nal status were variables significantly related to lower VD values (Winter-Spring p = 0.007; at risk of malnutrition p = 0.038).

Conclusions: The population who received supplementation presented a high frequency of VD deficiency and insufficiency which increases during winter and spring and in subjects at risk of malnutrition.

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Source
http://dx.doi.org/10.32641/andespediatr.v93i1.3377DOI Listing

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