Background: The topic of research was phenomenon of impaired age self-consciousness in non-psychotic latent schizophrenia patients defined.

Methods: The study sample comprised 141 patients with latent schizophrenia (pseudo neurotic (F21.3 - 64.5%, 91 patients), coenesthopathic (F20.8 - 25.5%, 36 patients) and pseudo psychopathic (F21.4 - 9.9%, 14 patients)) aged 16-31 (average 22.1 years old) in 2007-2019. A follow-up, experimental psychological and clinical study was conducted.

Results: The onset of impaired age self-identity was dominated by a radical drop of the subjective age in self-conscious mind of the patients accompanied by a tormented feeling of loss of self-dependence, role autonomy, helplessness, inability of decision making and to be answerable. Patients described this sudden condition as a loss of 'maturity feeling' and return to the juvenile perception of self. In a delusive and unclear manner, phrases such as 'I feel inferior to others as if a helpless child among adults', 'I feel as if my childhood is back' were uttered. Excessive worrying and enlivening of childhood memories were also included. This correlates to occurrence of humble and sometimes dependent/avoidant behavior, feeling of helplessness and fear with respect to caring for one self, rising subordination and suggestibility.

Conclusions: This phenomenon of regress to earlier ontogenetic level of personal development reported as impaired age self-consciousness can thus be regarded as an obligate form of depersonalization in patients with latent schizophrenia.

Download full-text PDF

Source

Publication Analysis

Top Keywords

latent schizophrenia
16
age self-consciousness
12
impaired age
12
patients
8
patients latent
8
age
5
impaired
4
impaired mental
4
mental age
4
latent
4

Similar Publications

Most psychiatric disorders are heterogeneous and are attributed to the synergistic action of a multitude of factors. It is generally accepted that psychiatric disorders are the outcome of interactions between genetic predisposition and environmental perturbations, which involve psychosocial stress, or alterations in the physiological state of the organism. A number of hypotheses have been presented on such environmental influences that may include direct insults such as injury, malnutrition and hostile living conditions, or indirect sequelae following infection from viruses such as influenza, arboviruses, enteroviruses and several herpesviruses, or the differential expression of human endogenous retroviruses.

View Article and Find Full Text PDF

Background: Impairments in theory of mind (ToM) are highly prevalent among individuals with schizophrenia, resulting in substantial functional deficits. However, research on impairments in individuals with schizotypy has yielded inconsistent findings, with some studies finding ToM deficits in overall schizotypy, other studies finding ToM deficits in only specific schizotypy dimensions, and yet other studies finding no ToM deficits at all. One potential key factor that may account for this discrepancy is the use of schizotypy measures that do not adequately measure specific schizotypy dimensions.

View Article and Find Full Text PDF

Background: The etiology of schizophrenia involves both biological and environmental risk factors. Studying childhood trauma in disorders along the schizophrenia spectrum, including schizotypal personality disorder (SPD), can inform early risk and protective factors for psychosis. However, no study has directly compared childhood trauma between SPD and schizophrenia.

View Article and Find Full Text PDF
Article Synopsis
  • The clinical high-risk (CHR) state for psychosis shows a lot of variability among individuals, causing challenges in treatment and research, especially since basic symptoms have often been overlooked.
  • The study assessed 875 patients from early intervention centers in Germany and Switzerland, using specific diagnostic tools to categorize their symptoms and demographics.
  • Results led to identifying three distinct clinical profiles: one with low symptom probability and high functioning, another with high basic and positive symptoms but low functioning, and a third mainly showing attenuated hallucinations, which can guide targeted interventions in future care.
View Article and Find Full Text PDF

Maternal Immune Activation and Endocannabinoid System: Focus on Two-Hit Models of Schizophrenia.

Biol Psychiatry

November 2024

Department of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy; Unit of Clinical Pharmacology, University Hospital, Cagliari, Italy; Neuroscience Institute, National Research Council of Italy, Section of Cagliari, Italy. Electronic address:

Article Synopsis
  • The COVID-19 pandemic highlights how infectious diseases can threaten society, especially during pregnancy, when infections can harm maternal health and increase the risk of neurodevelopmental disorders in children.
  • Maternal immune activation (MIA) from infections is linked to higher risks for disorders like autism and schizophrenia, supported by the two-hit hypothesis which suggests MIA could be the initial trigger for these conditions.
  • Research is examining how MIA interacts with cannabis use during adolescence, considering the endocannabinoid system's role in brain development, though findings show mixed results on whether cannabis exacerbates MIA-related issues in neurodevelopment.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!