Comparison of ocular biometry and refractive outcome between ANTERION and IOL Master 700.

Purpose: To assess the comparability of ocular biometry measurements and refractive outcomes between ANTERION and IOL Master 700.

Methods: This comparative prospective study was conducted from December 2020 to February 2021. A total of 225 patients who had cataracts were enrolled for the study and different parameters such as anterior keratometry (Steep K, Flat K) with axis, Sim K, central corneal thickness (CCT), aqueous depth (AQD), lens thickness (LT), and axial length (AL), white-to-white (WTW) were evaluated in IOL master 700 first and then with ANTERION. Finally, 203 patients completed the 6-week follow-up and the postoperative refraction was done at the 6 week. To assess the agreement between the devices, intraclass coefficient (ICC) and Bland-Altman analysis with 95% limits of agreement (LoA) were used. To analyze the agreement for postoperative residual refractive error between the two devices, Kappa statistics were used.

Results: The mean difference for steep K, flat K, and Sim K between ANTERION and IOL Master 700 were - 0.18 +/-0.26 D, -0.13+/- 0.28D, -0.15 +/-0.23, respectively. The CCT, ACD, and LT also showed excellent agreement (ICC > 0.9) but the similarity for the keratometry axis was not up to the mark (ICC = 0.794). For postoperative refractive outcomes, the Kappa value was 0.437, indicating moderate agreement.

Conclusion: : ANTERION showed a good agreement for the majority of parameters with IOLMaster 700 in measuring ocular biometry, except for the keratometry. The accuracy of the intraocular lens power calculations was clinically acceptable with both biometers though the IOL power given by ANTERION remained slightly on the hypermetropic side.