Massive, retracted rotator cuff tears with poor tissue quality continue to pose a problem for the shoulder surgeon. Augmentation of such repairs with grafts, patches, spacers, or biologics is being closely investigated to help improve clinical outcomes and healing rates. Specifically, superior capsule reconstruction augmentation of such rotator cuff tears may lead to good outcomes. However, we do not truly understand how much native cuff tissue or graft healing is actually taking place. Clinically, superior capsule reconstruction augmentation of rotator cuff repair may simply be serving as a spacer.
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http://dx.doi.org/10.1016/j.arthro.2021.12.021 | DOI Listing |
Pharmaceutics
January 2025
College of Pharmacy, Keimyung University, Daegu 42601, Republic of Korea.
/: Inhaler devices have been developed for the effective delivery of inhaled medications used in the treatment of pulmonary diseases. However, differing operating procedures across the devices can lead to user errors and reduce treatment efficacy, especially when patients use multiple devices simultaneously. To address this, we developed a novel dry powder inhaler (DPI), combining fluticasone propionate (FP), salmeterol xinafoate (SX), and tiotropium bromide (TB) into a single device designed for bioequivalent delivery compared to existing commercial products in an animal model.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Ophthalmology, UHC Sestre Milosrdnice, 10000 Zagreb, Croatia.
We describe a novel experimental device, the VaMa (Vatavuk and Marić) artificial intraocular lens (IOL) capsule, and a method that enables all IOL types to be implanted in the bag. We present the application of the device and the procedure in patients with aphakia and native capsule damage and without efficient capsular support. The VaMa device and the method facilitate IOL exchange due to refractive errors and, in the case of their invention, the implementation of superior IOLs in the future.
View Article and Find Full Text PDFBMC Psychiatry
January 2025
Shenzhen Children's Hospital, Shenzhen, 518000, China.
Objectives: The current study aimed to investigate the structural and functional connectivity of the subregions of the amygdala in children with Attention Deficit/Hyperactivity Disorder (ADHD) only or comorbid with Oppositional Defiant Disorder (ODD).
Methods: A total of 354 children with ADHD-only, 161 children with ADHD and ODD (ADHD + ODD), and 100 healthy controls were enrolled. The Child Behavior Checklist (CBCL) and the Behavior Rating Inventory of Executive Function (BRIEF) were filled out by caregivers.
Tomography
December 2024
Department of Computer Engineering, Faculty of Engineering, Karabük University, Karabük 78050, Türkiye.
Unlabelled: Due to the increasing number of people working at computers in professional settings, the incidence of lumbar disc herniation is increasing.
Background/objectives: The early diagnosis and treatment of lumbar disc herniation is much more likely to yield favorable results, allowing the hernia to be treated before it develops further. The aim of this study was to classify lumbar disc herniations in a computer-aided, fully automated manner using magnetic resonance images (MRIs).
J Knee Surg
January 2025
Department of Anesthesiology, The First Hospital of Jilin University, Changchun, People's Republic of China.
We aimed to compare the analgesic effects of intermittent multiple infiltrations between the popliteal artery and capsule of the posterior knee (IPACK) combined with adductor canal block (ACB) and intermittent ACB alone in patients with flexion contracture knee arthritis undergoing total knee arthroplasty (TKA). Forty-six patients who underwent elective unilateral TKA were divided into two groups ( = 23 each): intermittent multiple IPACK combined with ACB (group IA) and intermittent multiple ACB (group A). ACB was performed with 20 mL of 0.
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