Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/hep.32547 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
When HSFs bring the heat-mapping the transcriptional circuitries of HSF-type regulators in .
mSphere
December 2024
Institut Pasteur de Tunis, University of Tunis El Manar, Laboratoire de Microbiologie Moléculaire, Vaccinologie et Développement Biotechnologique, Tunis, Tunisia.
Heat shock factor (HSF)-type regulators are stress-responsive transcription factors widely distributed among eukaryotes, including fungi. They carry a four-stranded winged helix-turn-helix DNA-binding domain considered as the signature domain for HSFs. The genome of the opportunistic yeast encodes four HSF members, namely, Sfl1, Sfl2, Skn7, and the essential regulator, Hsf1.
View Article and Find Full Text PDFGenCOLT: a multicenter European biobank for investigating genome-wide determinants of lung transplant outcomes.
Eur J Hum Genet
November 2024
Division of Transplantation, Department of Surgery, New York University Langone Health, New York, NY, USA.
H4K20me3-Mediated Repression of Inflammatory Genes Is a Characteristic and Targetable Vulnerability of Persister Cancer Cells.
Cancer Res
January 2025
Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Anticancer therapies can induce cellular senescence or drug-tolerant persistence, two types of proliferative arrest that differ in their stability. While senescence is highly stable, persister cells efficiently resume proliferation upon therapy termination, resulting in tumor relapse. Here, we used an ATP-competitive mTOR inhibitor to induce and characterize persistence in human cancer cells of various origins.
View Article and Find Full Text PDFExploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis.
JAMA Cardiol
November 2024
St John's Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.
Article Synopsis
- The study investigates the complex relationship between immune-mediated diseases (IMIDs), like psoriasis, and cardiovascular diseases (CVDs), such as coronary artery disease (CAD) and stroke, focusing on genetic factors.
- It employs Mendelian randomization to analyze data from large genome-wide association studies (GWAS) to establish potential causative links between psoriasis and these cardiovascular conditions.
- The analysis encompasses nearly 3.4 million individuals, providing insights into how genetic predictors of CAD and stroke may influence the risk of developing psoriasis and nine other IMIDs.
Commentary: The causal effect of hypertension, intraocular pressure, and diabetic retinopathy: a Mendelian randomization study.
Front Endocrinol (Lausanne)
September 2024
Health Science Center, Yangtze University, Jingzhou, Hubei, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!