AI Article Synopsis
- - A female patient with OCD received bilateral stimulation of the subthalamic nucleus (slMFB DBS) to treat her condition over a 35-month period.
- - She experienced right leg dyskinesia due to unintended stimulation of the nearby anteromedial subthalamic nucleus (amSTN).
- - After adjusting the stimulation away from the amSTN towards the mesencephalic ventral tegmentum (MVT), the dyskinesia resolved while still effectively managing her OCD symptoms.
Article Abstract
Here we describe therapeutic results in a female patient who underwent bilateral slMFB DBS for OCD. During a 35-month long course of stimulation, she suffered from stimulation-induced dyskinesia of her right leg which we interpreted as co-stimulation of the adjacent anteromedial subthalamic nucleus (amSTN). After reprogramming to steer the stimulation away from the amSTN medial into the direction of the mesencephalic ventral tegmentum (MVT which contains the ventral tegmental area, VTA), the dyskinesias disappeared. Remarkably, anti-OCD efficacy in the presented patient was preserved and achieved with a bilateral stimulation which by our imaging study fully avoided the amSTN.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427876 | PMC |
| http://dx.doi.org/10.1007/s00701-022-05206-w | DOI Listing |
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