AI Article Synopsis
- The study identified and measured total protein, phenolic, and flavonoid content, and analyzed the phenolic profile related to antioxidant and antidiabetic activities of ethanolic (EtOH) and water extracts of certain plant species.
- Water extracts showed the highest ability to scavenge free radicals like DPPH˙ and O˙, while EtOH extracts exhibited better results against NO˙.
- Histological examinations indicated that the extracts have protective effects on pancreatic tissue, suggesting they could be promising candidates for further research into their antidiabetic properties.
Article Abstract
This study was designed to define total protein, phenol and flavonoid content as well as LC-MS/MS phenolic profile related to antioxidant and antidiabetic activity of ethanolic (EtOH) and water extracts of and . water extract possessed the highest ability to scavenge DPPH˙ and O˙, while the EtOH extract of the same species showed better activity on NO˙ related to other extracts. The highest level of bioactive compounds was determined generally in EtOH extracts. Antidiabetic action was evaluated by the oral glucose tolerance test (OGTT) and histological examination of pancreas and liver in normoglycemic and alloxan-induced diabetic animals. Histological examination of pancreatic tissue demonstrated that extracts have protective effects. To conclude, analysed extracts could be considered as a promising candidate for further research with the aim to promote antidiabetic activity, which is for the first time reported for .
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050389 | PMC |
| http://dx.doi.org/10.1039/c9ra10158f | DOI Listing |
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