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An approach to new chiral bicyclic imines and amines Horner-Wadsworth-Emmons reaction. | LitMetric

New chiral bicyclic imines, enamines and amines were prepared Horner-Wadsworth-Emmons reaction of hexahydroquinoxalin-2(1)-one-derived phosphonate, as the source of a phosphonate carbanion, and a wide range of structurally diverse carbonyl substrates. The simplicity of the synthetic protocol, high selectivity, and broad substrate scope are the main advantages of the presented methodology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052066PMC
http://dx.doi.org/10.1039/d0ra02646hDOI Listing

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