Growth of species is inhibited by free fatty acids and bile salts but not by glycerides.

AIMS Microbiol

Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA.

Published: March 2022

High-fat diets have been associated with lower gut and fecal abundances of genus . Here, we investigated whether commonly consumed dietary free fatty acids have any detrimental effect on the growth of , , and . We found that the presence of free fatty acids in the medium inhibits the growth of species to a varying degree, with capric (C10:0), oleic (C18:1), and linoleic (C18:2) acids displaying the largest effect. In comparison, free fatty acids did not affect the growth of . When fats were added as a mixture of mono- and diacylglycerols, the inhibitory effect on growth was abolished.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995189PMC
http://dx.doi.org/10.3934/microbiol.2022005DOI Listing

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