Viral infections emerge in the pathogenesis of subacute thyroiditis. Aside from this, subacute thyroiditis following vaccines utilizing inactivated viruses has been shown on rare occasions. Due to the COVID-19 pandemic, several vaccines have been developed all over the world; mass and unprecedented vaccination has thus been initiated. However, it is known that cases such as subacute thyroiditis have been reported, albeit rarely, after administration of COVID-19 vaccines. In this case report, we present a 59-year-old patient with multiple myeloma developing subacute thyroiditis following BNT162b2 vaccine. Patient had swelling in the neck, and his symptoms were controlled with non-steroidal anti-inflammatory drugs. Subacute thyroiditis following administration of the COVID-19 vaccine is rare; however, it is likely an under-reported condition that is difficult to detect. Clinicians should stay informed and have increased awareness of post-COVID-19 vaccine subacute thyroiditis.
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http://dx.doi.org/10.1177/2050313X221091392 | DOI Listing |
J Clin Endocrinol Metab
January 2025
Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Objective: Subacute thyroiditis (SAT) is a painful inflammatory disorder of the thyroid gland, which - after a phase of thyrotoxicosis - leads to transient, or less frequently permanent hypothyroidism. Apart from a strong association with specific HLA alleles, the causes are uncertain. Viral disease has been hypothesised as a trigger, with Enteroviruses, namely Echoviruses and Coxsackieviruses, showing a seasonal distribution that coincides with the incidence of SAT.
View Article and Find Full Text PDFEndocr Connect
January 2025
H Qu, Department of Endocrinology, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Subacute thyroiditis (SAT) is an inflammatory thyroid disease characterized by neck pain, tenderness, general symptoms, and thyroid dysfunction. Despite gaining new insights into the epidemiology, pathogenesis, and treatment of SAT in recent years, the exact pathogenesis and determinants of its clinical progression remain unclear. Here, we profiled thyroid in situ protein alterations in fine needle aspiration biopsy samples from SAT patients using proteomic analysis and uncovered 57 differentially abundant proteins.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
December 2024
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Data Brief
December 2024
Universidad Nacional de Asunción, Facultad Politécnica, San Lorenzo 111421, Paraguay.
This article presents a dataset containing 641 images of Thyroid Gammagraphies studies corresponding to 235 patients over 18 years of age that were acquired in the period from 2016 to 2024 at the Nuclear Medicine Service of the of the (IICS - UNA), Paraguay. First, the Thyroid Gammagraphies images were acquired according to the acquisition protocol described in this article. The thyroid scintigraphies images were acquired using trimodal SPECT-CT-PET equipment, model AnyScan SCP, MEDISO brand.
View Article and Find Full Text PDFJ Transl Autoimmun
December 2024
Department of Nuclear Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaan Xi Province, 710004, China.
Background: Since the end of the COVID-19 pandemic, the potential roles of thyroid-inflammatory derangements in driving or being associated with the prognosis of COVID-19 remain controversial. We aimed to clarify the association between COVID-19 infection and thyroid dysfunction, and highlight the impacts of subsequent autoimmune thyroid disease (AITD) on the prognosis of COVID-19.
Methods: The retrospective, multicenter, cohort study enrolled 2,339 participants with COVID-19 from three hospitals located in the north, middle, and south regions of Shaan Xi Province, China, between December 2022 and July 2023.
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