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Synthesis of natural 1--alkylglycerols: a study on the chemoselective opening of the epoxide ring by onium quaternary salts (N and P) and ionic liquids. | LitMetric

Synthesis of natural 1--alkylglycerols: a study on the chemoselective opening of the epoxide ring by onium quaternary salts (N and P) and ionic liquids.

RSC Adv

Laboratório de Síntese e Análise de Produtos Estratégicos-Centro de Tecnologia, Departamento de Química Analítica, Instituto de Química, Universidade Federal do Rio de Janeiro Bloco A, S. 508 Rio de Janeiro-RJ CEP 21941-909 Brazil

Published: January 2020

AI Article Synopsis

  • The paper presents a method for synthesizing 1-alkylglycerols chimyl, batyl, and selachyl, which can be derived from shark liver oil and certain animal skins.
  • These compounds show potential for anti-fouling applications, which could be valuable in various industries.
  • The synthesis involves two main techniques: solvent-free reactions using onium quaternary salts and ionic liquids, as well as a series of one-pot reactions.

Article Abstract

A chemoselective route for the synthesis of 1--alkylglycerols chimyl (1), batyl (2), and selachyl (3) is reported. These compounds can be naturally isolated from shark liver oil and the skin of animals such as stingrays and chimeras and exhibit potential anti-fouling activity. The synthetic approach developed in this work included two distinct methods of preparation. The first was based on solvent-free reactions catalyzed by onium quaternary salts (N and P) and ionic liquids; the second methodology was based on a series of one-pot reactions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047497PMC
http://dx.doi.org/10.1039/c9ra09217jDOI Listing

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