Bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN alcohol) is the most prominent strained-alkyne scaffold in chemical biology. Described herein is the synthesis of an oxidized analogue - BCN acid - whose facile functionalization amide bond formation yields more stable derivatives than the classically encountered carbamates.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043778 | PMC |
| http://dx.doi.org/10.1039/d1ra07905k | DOI Listing |
Publication Analysis
Top Keywords
bicyclo[610]nonyne carboxylic
4
carboxylic acid
4
acid production
4
production stable
4
stable molecular
4
molecular probes
4
probes bicyclo[610]non-4-yn-9-ylmethanol
4
bicyclo[610]non-4-yn-9-ylmethanol bcn
4
bcn alcohol
4
alcohol prominent
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!