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High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma - a case report. | LitMetric

AI Article Synopsis

  • The report details a case of an 87-year-old woman with metastatic extraskeletal myxoid chondrosarcoma (EMC) who underwent treatment after her initial surgical amputation for a large tumor in her ankle.
  • High-dose-rate interstitial brachytherapy (HDR-ISBT) was administered to manage metastases in her inguinal lymph node, breast, and popliteal fossa, providing significant control over the tumors.
  • The HDR-ISBT treatment (30 Gy/2 fractions in 1 day) proved effective for palliative care and long-term control of the disease without severe side effects.

Article Abstract

We report on a patient with metastatic extraskeletal myxoid chondrosarcoma (EMC), who was treated with palliative high-dose-rate (HDR) interstitial brachytherapy (ISBT). The patient was an 87-year-old woman who underwent an amputation for a bulky tumor in her right ankle joint. EMC was histopathologically confirmed. She presented with a large right inguinal lymph node metastasis of EMC 16 months after surgery. Palliative HDR-ISBT (30 Gy/2 fractions in 1 day) for the right inguinal lymph node metastasis was administered to shorten treatment period. Additional HDR-ISBT (30 Gy/2 fractions in 1 day) was administered for the management of subsequent subcutaneous metastasis to the right breast and right popliteal fossa. HDR-ISBT provided significant long-term control of the recurrent tumor in all three sites, without severe acute and late toxicity. Thus, HDR-ISBT regimen of 30 Gy/2 fractions in 1 day can be a suitable option for both palliation and long-term local control for patients with metastatic EMC.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044308PMC
http://dx.doi.org/10.5114/jcb.2022.115161DOI Listing

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