Biomimetic synthetic functional materials are valuable for a large number of practical applications with improved or tunable performance. In this paper, we present a series of mussel-inspired biomimetic catechol-containing copolymers synthesized from dopamine methacrylamide (DMA) and 2-(2-ethoxyethoxy)ethyl acrylate (EEA) and abbreviated as poly(PDMA-PEEA). The successfully synthesized adhesive polymers allow adhering polytetrafluoroethylene (PTFE) and were used for coating PTFE particles in organic solvent and re-dispersion in an aqueous medium. Adhesive polymer coated PTFE particles were efficiently used as a nanoreactor for generating silver (Ag) metal nanoparticles (NPs).
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http://dx.doi.org/10.1039/c9ra10606e | DOI Listing |
Angew Chem Int Ed Engl
January 2025
Sree Chitra Tirunal Institute for Medical Sciences and Technology, Bioceramics Division, Biomedical Technology Wing, 695011, Thiruvananthapuram, INDIA.
A collagen-inspired helical protein-mimic has been synthesized via topochemical polymerization of a designed tripeptide monomer. In the monomer crystal, molecules arrange in a head-to-tail manner, forming supramolecular helices. The azide and alkyne of adjacent molecules in the supramolecular helix are proximally preorganized in a ready-to-react arrangement.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
PRISM Research Institute, Technological University of the Shannon: Midlands Midwest, Athlone, Ireland.
This study provides a comprehensive investigation of antimicrobial additives (ZnO/AgNPs and SiO/AgNPs) on the properties of biodegradable ternary blends composed of poly(hydroxybutyrate) (PHB), poly(lactic acid) (PLA), and polycaprolactone (PCL) by examining the morphology, thermal stability, crystallinity index, and cell viability of these blends. Overall, transmission electron microscopy (TEM) analysis revealed that AgNPs and SiO exhibited comparable sizes, whereas ZnO was significantly larger, which influences their release profiles and interactions with the blends. The addition of antimicrobials influences the rheology of the blends, acting as compatibilizers by reducing the intermolecular forces between biopolymers.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Xiangya Stomatological Hospital and Xiangya School of Stomatology, Central South University; Hunan Engineering Research Center for Oral Digital Intelligence and Personalized Medicine; Hunan 3D Printing Engineering Research Center of Oral Care; WANG Songling Academician Workstation for Oral-maxilofacial and Regenerative Medicine, Central South University, Changsha 410078.
Objectives: Drug-loaded mucoadhesive silk fibroin (SF) microneedle patch can overcome the limitations of low bioavailability and significant pain associated with traditional treatment methods, such as topical application or injection of triamcinolone for oral submucous fibrosis (OSF). However, these systems release the drug too quickly, failing to meet the clinical requirements. This study aims to construct a mucoadhesive SF microneedle patch pre-assembled with silk fibroin nanospheres (SFN) and explore its ability to sustain the release of triamcinolone in the treatment of OSF.
View Article and Find Full Text PDFJ Control Release
January 2025
Department of Bioengineering and Nano-Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea; Research Center for Bio Materials & Process Development, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea. Electronic address:
Delayed wound healing remains a major challenge in biomedical research, often leading to complications such as scarring, acute trauma, and chronic diseases. Effective wound management is crucial for enhancing treatment outcomes, preventing complications, and promoting tissue regeneration. In response to this need, a variety of polymeric biomaterials have been developed.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Safety and Environmental Engineering, Shandong University of Science and Technology, Qingdao 266590, China; State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology, Shandong University of Science and Technology, Qingdao 266590, China.
To effectively utilize sesbania gum in coal dust control and address the limitations of excessive viscosity and mediocre strength, oxidation treatment was used to improve its fluidity. Polyvinyl alcohol (PVA) and sodium trimetaphosphite (STMP) were used to enhance oxidized sesbania gum OSG, and crosslinking technology was used to improve its mechanical stability. This study developed a novel foam dust suppressant OSG-PVA/SDBS by response surface design, and the optimized dust suppressant material exhibited excellent adhesion and curing properties.
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