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Genital Herpes: Rapid Evidence Review.
Am Fam Physician
November 2024
Eglin Air Force Base Family Medicine Residency Program in Florida.
Article Synopsis
- - Genital herpes, caused by herpes simplex virus (HSV) types 1 or 2, is a lifelong sexually transmitted infection affecting over 500 million people globally, with no available vaccines for prevention.
- - It is characterized by painful genital lesions and flu-like symptoms; diagnosis is typically made through laboratory tests like PCR or viral culture.
- - Treatment includes antiviral medications to manage outbreaks and reduce transmission, and pregnant individuals with a history of genital herpes are advised to start antiviral therapy at 36 weeks and may require a cesarean section if lesions are present.
Prophylactic antibiotics for manual removal of retained placenta in vaginal birth.
Cochrane Database Syst Rev
October 2024
Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Rationale: Retained placenta is a potentially life-threatening condition because of its association with postpartum haemorrhage. Manual removal of the placenta increases the likelihood of infectious complications of the uterine cavity. So, prophylactic antibiotics are recommended by some experts, and commonly administered to reduce these risks.
View Article and Find Full Text PDFClinical practices in the management and follow-up of obstetric anal sphincter injuries: a comprehensive review.
Eur J Obstet Gynecol Reprod Biol
November 2024
Service de chirurgie gynécologique, CHU Lille, Lille F-59000, France; Faculté de médecine, Univ. Lille, Lille F-59000, France; Univ. Lille, CNRS, Centrale Lille, UMR 9013 - LaMcube - Laboratoire de Mécanique, Multiphysique, Multiéchelle, Lille F-59000, France.
Objectives: To review and compare existing guidelines on the intrapartum management and postpartum follow-up of obstetric anal sphincter injuries (OASIS) METHODS: We conducted a systematic review of clinical guidelines related to OASIS management, focusing on intrapartum care and postpartum follow-up. Searches were performed in July 2024 across multiple databases, including PubMed, Embase, and the Cochrane Library. Guidelines published after 2010 in English were included.
View Article and Find Full Text PDFPlacental cord drainage impact on third stage of labor: a randomized controlled trial.
Am J Obstet Gynecol MFM
October 2024
Helen Schneider Hospital for Women, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel (Hendin, Grosvald, Shemesh, Leonenko, Segal, Geron, Borovich, Hadar, Walfisch, and Houri); Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (Hendin, Grosvald, Shemesh, Leonenko, Jbara, Segal, Geron, Chen, Hadar, Walfisch, and Houri).
Background: The third stage of labor is a pivotal phase in obstetric care. Management may be physiological or active. Although the use of prophylactic placental cord drainage has been assessed in prior data, there is still no clear-cut evidence supporting its effectiveness in improving key obstetric outcomes.
View Article and Find Full Text PDFTransperineal Versus Transrectal Magnetic Resonance Imaging-targeted Prostate Biopsy: A Systematic Review and Meta-analysis of Prospective Studies.
Eur Urol Oncol
December 2024
Unit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Background And Objective: The benefits of the detection of clinically significant prostate cancer (csPCa) and safety of magnetic resonance imaging (MRI)-targeted transperineal (TP) prostate biopsy (TP-Tbx) versus transrectal (TR) approaches are still a matter of debate. This review aims to compare the efficacy and safety of TP-Tbx and MRI-targeted TR biopsy (TR-Tbx).
Methods: A systematic literature search was performed in PubMed/Medline, Scopus, and Web of Science to identify records of prospective randomized controlled trials (RCTs) comparing TP-Tbx and TR-Tbx published until May 2024.
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