Long-term follow-up of complicated monochorionic twin pregnancies: Focus on neurodevelopment.

Best Pract Res Clin Obstet Gynaecol

Willem-Alexander Children's Hospital, Department of Pediatrics, Division of Pediatric Psychology, Leiden University Medical Center, Leiden, the Netherlands.

Published: November 2022

Monochorionic twin pregnancies have an increased risk of morbidity and mortality. Due to the advancements in screening and treatment strategies, mortality rates have decreased. Improving survival rates demands a shift in scope toward long-term outcomes. In this review, we focus on neurodevelopmental outcome in survivors from complicated monochorionic twin pregnancies, including twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS), acute peripartum TTTS, acute perimortem TTTS, selective fetal growth restriction (sFGR) and monoamnionicity. Our aim is to provide an overview of the current knowledge on the long-term outcome in survivors, including psychomotor development and quality of life, and provide recommendations for future research and follow-up programs.

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http://dx.doi.org/10.1016/j.bpobgyn.2022.03.014DOI Listing

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