AI Article Synopsis

  • Primary hyperparathyroidism (PHPT) in pregnancy is uncommon but can lead to serious health issues for both the mother and baby.
  • A case study describes a 32-year-old woman who underwent successful parathyroid surgery at 36 weeks of pregnancy due to severe hypercalcemia.
  • The surgery was well-tolerated, and she later delivered a healthy baby girl, with the newborn experiencing only mild postnatal hypocalcemia.

Article Abstract

Primary hyperparathyroidism (PHPT) in pregnancy is rare and may be associated with increased maternal and fetal morbidity and mortality. The ideal timing for parathyroidectomy is during the second trimester, and parathyroidectomy in the third trimester is extremely rare. We present a case of a 32-year-old woman who was admitted to our hospital with severe hypercalcemia in the 36th week of her first pregnancy. Conventional bilateral neck exploration was performed and parathyroid adenoma was removed. The surgical procedure was tolerated well by the mother, and she delivered a healthy girl 10 days after surgery. The newborn had mild hypocalcemia that required minimal substitution postnatally; however, no tetany occurred. This case demonstrates that parathyroidectomy in the third trimester followed by spontaneous delivery may be performed safely.

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