[Adverse events/adverse reactions of acupoint catgut embedding therapy for psoriasis vulgaris: a systematic review].

Zhen Ci Yan Jiu

The Second School of Clinical Medicine of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120; State Key Laboratory of Moisture Syndrome of traditional Chinese medicine, Guangzhou 510120; Guangdong-Hong Kong-Macao Joint Laboratory of traditional Chinese medicine and Immune Diseases Research, Guangzhou 510120; Key Laboratory of traditional Chinese medicine Syndrome Clinical Research of Guangdong Province, Guangzhou 510120.

Published: April 2022

AI Article Synopsis

  • The study aimed to review the safety and occurrence of adverse events (AEs) associated with acupoint catgut embedding therapy used to treat psoriasis vulgaris (PV).
  • A total of 16 studies with 1,158 patients were analyzed, revealing 79 cases of mild to moderate AEs linked to the therapy, with no serious adverse effects reported.
  • The most common AEs included local redness, swelling, and pain, suggesting the need for caution and standardized guidelines in clinical practice to minimize risks.

Article Abstract

Objective: To systematically review the occurrence of adverse events/adverse reactions (AEs/ARs) induced by acupoint catgut embedding therapy for psoriasis vulgaris (PV) and its safety.

Methods: Randomized controlled trials, controlled clinical trials, cohort studies, case-control studies, case-series, and case reports concerning the treatment of PV with acupoint catgut embedding therapy were searched from Chinese and English databases from their inception to January 7, 2021. The AEs/ARs related to acupoint catgut embedding therapy for PV were subjected to descriptive statistics, followed by the analysis of possible reasons.

Results: Finally, 16 studies were included, involving 1 158 patients. A total of 79 cases were reported to present with mild to moderate AEs/ARs related to acupoint catgut embedding therapy for PV, and there were no serious AEs/ARs or death cases. The most common AEs/ARs were local redness, swelling, heat, and pain (31.65%,25/79), followed by low-grade fever and fatigue (29.11%,23/79), isomorphic reaction (16.46%,13/79), local induration (13.92%,11/79), and fainting (8.86%,7/79). In terms of embedding materials, catgut (93.67%,74/79) and lumbar puncture needles or other puncture needles (49.37%,39/79) were proved the most common AEs/ARs-inducing factors. The proportion of AEs/ARs resulting from treatment interval≤two weeks (67.09%,53/79) and treatment course≤eight weeks (55.70%,44/79) was relatively high. Because the incidence of AEs/ARs fails to be calcula-ted, it is not yet possible to accurately assess the risk and safety of acupoint catgut embedding therapy for PV.

Conclusion: Available evidence suggests that in the treatment of PV, acupoint catgut embedding therapy may induce a series of mild to moderate AEs/ARs, so its clinical practice deserves attention. We should strictly grasp its indications and contraindications, and prevent the occurrence of related AEs/ARs by standardizing the operation and improving the embedding materials.

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http://dx.doi.org/10.13702/j.1000-0607.20210077DOI Listing

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