Sporadic extranodal Rosai-Dorfman-Destombes disease treated with tocilizumab.

Pediatr Blood Cancer

Nemours Center for Cancer and Blood Disorders, Nemours Children's Hospital - Delaware, Wilmington, Delaware, USA.

Published: December 2022

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.29754DOI Listing

Publication Analysis

Top Keywords

sporadic extranodal
4
extranodal rosai-dorfman-destombes
4
rosai-dorfman-destombes disease
4
disease treated
4
treated tocilizumab
4
sporadic
1
rosai-dorfman-destombes
1
disease
1
treated
1
tocilizumab
1

Similar Publications

Burkitt's lymphoma with multi-organ involvement.

Int J Surg Case Rep

December 2024

Department of Pathology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Article Synopsis
  • Burkitt's lymphoma (BL) is a fast-growing B-cell non-Hodgkin lymphoma that often affects multiple organs, including rare cases in the gastrointestinal tract, which makes up less than 2% of small intestinal cancers.!* -
  • A 34-year-old man with sickle cell trait showed symptoms like abdominal pain and weight loss, and after imaging and surgery, he was diagnosed with Burkitt's lymphoma that affected his cecum, appendix, peritoneum, and bone marrow.!* -
  • The case emphasizes the significance of recognizing the fast progression of BL and the "starry sky" pattern in histopathology for accurate diagnosis and correlation in clinical settings.!*
View Article and Find Full Text PDF

Background: Conceptually, thyroid tumor desmoplasia may be better suited for excluding node metastases in sporadic MTC than preoperative serum calcitonin levels.

Methods: This analysis included 181 patients with unilateral sporadic MTC graded on the 7-grade desmoplasia scale after thyroidectomy and neck dissection.

Results: When thyroid tumor desmoplasia reached 1% and ≥50%, node metastases increased from 0% to 7% (median of 0 metastases) and 83% (median of 7.

View Article and Find Full Text PDF

Burkitt lymphoma is a highly invasive non-Hodgkin lymphoma. Sporadic Burkitt's lymphoma is commonly found in the abdomen. However, Burkitt lymphoma infiltrating the uterus is uncommon in occurrence.

View Article and Find Full Text PDF

Background: While primary tumor desmoplasia is a powerful biomarker of node metastases in sporadic medullary thyroid cancer (MTC), information for hereditary MTC is sparse.

Methods: This proof-of-concept study, comprising 3 consecutive children with multiple endocrine neoplasia 2B, evaluated simultaneously the metastatic behavior of multiple primary thyroid tumors of disparate size and extent of desmoplasia within patients.

Results: Altogether, MTC typically involved the ipsilateral central neck before spreading to the ipsilateral lateral and the contralateral neck.

View Article and Find Full Text PDF

Non-Hodgkin lymphoma is made from the B-cell lineage and includes extra-nodal marginal lymphomas, follicular lymphomas, mantle cell lymphoma, diffuse large B-cell lymphoma, and Burkitt lymphoma. Burkitt lymphoma is associated with Epstein Barr Virus and Human Immunodeficiency Virus. Although it is common for other B-cell lymphomas to develop in the stomach, it is less common for Burkitt lymphoma tumors to manifest there.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!