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CPAP delivered via a helmet interface in lightly sedated patients with moderate to severe ARDS: predictors of success outside the ICU.
J Bras Pneumol
December 2024
. Departamento de Medicina Interna, Universidade Federal do Ceará, Fortaleza (CE) Brasil.
Objective: This study aimed to describe the outcomes and explore predictors of intubation and mortality in patients with ARDS due to COVID-19 treated with CPAP delivered via a helmet interface and light sedation.
Methods: This was a retrospective cohort study involving patients with COVID-19-related ARDS who received CPAP using a helmet developed in Brazil (ELMO™), associated with a light sedation protocol in a pulmonology ward. Demographic, clinical, imaging, and laboratory data, as well as the duration and response to the ELMO-CPAP sessions, were analyzed.
High flow nasal cannula and low level continuous positive airway pressure have different physiological effects during de novo acute hypoxemic respiratory failure.
Ann Intensive Care
November 2024
Groupe de Recherche Clinique CARMAS, Faculté de Santé, Université Paris Est-Créteil, Créteil Cedex, 94010, France.
Background: Large tidal volumes during de novo acute hypoxemic respiratory failure (AHRF) may promote patient self-inflicted lung injury. Tidal volume assessment under high flow nasal cannula (HFNC) is not routinely feasible at the bedside. Our objective was to determine whether tidal volume during low-level continuous positive airway pressure (CPAP) could predict tidal volume during HFNC and to compare the physiological effects of HFNC and low-level CPAP.
View Article and Find Full Text PDFPhosphorylated octa-aminopropyl POSS grafting on proanthocyanidin interface decorated 2D MXene for enhanced flame-retardancy of cotton fabric nanocomposites.
Int J Biol Macromol
December 2024
Key Laboratory of Eco-textiles, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China. Electronic address:
Two-dimensional (2D) nanosheet materials (MXenes) have unparalleled advantages in the field of flame-retardant multifunctional composites, but their dispersibility, flame retardancy and compatibility with the matrix are poor and need to be enhanced. In this research, we employed interfacial decoration and grafting modification to firstly introduce proanthocyanidins (PCs) onto MXenes surface (forming PC-MXenes) to increase the number of available active sites. On this basis, phosphorylated A-POSS was grafted onto PC-MXene (resulting in PAP@P-MXene) via a one-pot method, organic-inorganic hybrid flame-retardant PAP@P-MXene nano-coatings were subsequently constructed on the surface of cotton fabrics via an immersion method, and their structure-property relationships were verified.
View Article and Find Full Text PDFThe effects of noninvasive respiratory support on swallowing physiology, airway protection, and respiratory-swallow pattern in adults: A systematic review.
Respir Med
November 2024
Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, Illinois, USA; Department of Otolaryngology-Head and Neck Surgery and Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Edward J. Hines, Jr. Veterans Affairs Medical Center, Hines, Illinois, USA.
Purpose: The use of noninvasive respiratory support- namely high flow of oxygen delivered via nasal cannula (HFNC), continuous positive airway pressure (CPAP), and noninvasive ventilation (NIV) - has been expanding in recent years. The physiologic mechanisms underlying each of these forms of support are generally well understood. In contrast, the effects on the sensorimotor mechanisms of swallowing movements, and of breathing and swallowing coordination ─ critical elements of airway protection and bolus clearance ─ remain unclear.
View Article and Find Full Text PDFMAPK pathway and NIS in B-CPAP human papillary thyroid carcinoma cells treated with resveratrol.
Pathol Res Pract
November 2024
Department of Endocrinology and Metabolism, Ege University School of Medicine, Izmir, Turkey. Electronic address:
Background: Resveratrol, a herbal phytoalexin, is known to have anti-tumor effects in several tumors including thyroid cancer cells.
Aim: The aim of this study was to determine the effects of resveratrol on the expression of BRAF, ERK and NIS mRNA levels and protein expression in B-CPAP human thyroid papillary cancer cell line.
Methods: B-CPAP cells were treated with resveratrol at concentrations of 10-100 μM for 24-48-72 h.
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