Introduction: The objective of this manuscript is to outline the process involved in the development and validation of a survey that is optimal for assessing the impact of a substance use disorder (SUD) elective course.
Methods: Face validation was performed once the initial survey was developed. Additionally, field validation was performed by surveying a small population of pharmacy students enrolled in the elective course. Non-parametric chi-square test and factor analysis were performed to analyze survey results and measure survey validity, while Cronbach alpha (CA) was performed to measure reliability.
Results: Student survey responses showed a significance of P < .05 using one sample chi-square test for statements 1, 5, 6, 7, 8, 11, 12, 13, and 15. Factor analysis identified five factors; however, only three factors were identified as having good correlation. Factor 1 related to students' beliefs about patients with SUD, factor 2 related to attitudes about patients with SUD, and factor 3 related to beliefs about SUD. Factors 1, 2, and 3 have a calculated CA > 0.7, indicating strong internal consistency and reliability.
Conclusions: Some of the original statements loaded as expected and assessed the impact of the course in shaping students' beliefs and attitudes regarding SUD. However, some statements did not load as expected, and the survey was modified in order to better assess the desired endpoints.
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http://dx.doi.org/10.1016/j.cptl.2022.03.012 | DOI Listing |
J Agric Food Chem
January 2025
College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
T-2 toxin is a highly toxic fungal toxin that threatens humans and animals' health. As a major detoxifying and metabolic organ, the kidney is also a target of T-2 toxin. This article reviews T-2 toxin nephrotoxicity research progress, covering renal structure and function damage, nephrotoxicity mechanisms, and detoxification methods to future research directions.
View Article and Find Full Text PDFEur J Drug Metab Pharmacokinet
January 2025
Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
Caffeine consumption is regarded as a widespread phenomenon, and its usage has continued to increase. In addition, the growing usage of antidepressants worldwide and increase in mental health disorders were shown in recent statistical analyses conducted by the World Health Organisation. The coadministration of caffeine and antidepressants remains a concern due to potential interactions that can alter a patient's response to therapy.
View Article and Find Full Text PDFInt J Pharm
January 2025
Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States. Electronic address:
For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they are often followed by one or more biosimilar products. These biosimilars often differ from the innovator product, as well as from each other, in their formulation composition. However, the impact of the formulation composition on the stability of the active pharmaceutical ingredient subjected to different 'stresses' is still not understood.
View Article and Find Full Text PDFNicotine Tob Res
January 2025
Behavioral Health and Health Policy, Westat, 1600 Research Blvd, Rockville, MD 20850, United States.
Introduction: Pregnant people who smoke constitute a uniquely vulnerable population likely to be impacted by a menthol cigarette (MC) ban. However, there are no published reports of prevalence of prenatal MC use in a nationally-representative US sample including racial-ethnic disparities and associated characteristics.
Methods: Participants were 1245 US pregnant people who smoked MC or non-MC (NMC) in the past 30-days from the 2010-2019 National Survey on Drug Use and Health.
J Food Sci Technol
February 2025
Present Address: School of Food and Health, Beijing Technology and Business University, 11 Fucheng Road, Beijing, 100048 China.
Unlabelled: Fermented foods, especially those derived from cereals, are significant contributors to the diversification of global diets. As people pay increasing attention to food taste, flavor, and nutritional balance, conducting a comprehensive and integrated evaluation of the role of fermentation technology in cereals has become a top priority. This article reviews relevant research conducted in recent years, summarizing the fermentation conditions of cereals and focusing on the effects of fermentation on the nutritional value and health benefits of cereals, including its impact on basic components such as starch and dietary fiber.
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