An iron porphyrin-catalyzed -trifluoroethylation of anilines has been developed with 2,2,2-trifluoroethylamine hydrochloride as the fluorine source. This one-pot N-H insertion reaction is conducted cascade diazotization/-trifluoroethylation reactions. The developed transformation can afford a wide range of -trifluoroethylated anilines in good yields using readily available primary amines and secondary anilines as starting materials.
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| http://dx.doi.org/10.1039/d1ra03379d | DOI Listing |
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