A chiral heterogeneous catalyst derivative of (-)-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2-benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out in a deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity is excellent. The catalyst was easily recovered and reused with no decrease in its catalytic activity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037113PMC
http://dx.doi.org/10.1039/d1ra05297gDOI Listing

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