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Temporal Trends in Hippocampal Sclerosis Surgery: An Observational Study From a Tertiary Epilepsy Centre.
Eur J Neurol
January 2025
Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK.
Objective: Temporal lobe epilepsy with hippocampal sclerosis (HS) is a surgically remediable syndrome. We determined temporal trends in the prevalence of hippocampal sclerosis surgeries and related factors.
Methods: We analysed a prospective cohort of adults who underwent epilepsy surgery at the NHNN, London, between 1990 and 2019.
Replication timing (RT) allows us to analyze temporal patterns of genome-wide replication, i.e., if genes replicate early or late during the S-phase of the cell cycle.
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Local Environ
November 2024
SOPPECOM - Society for Promoting Participative Ecosystem Management, Pune, India.
This paper develops the methodological concept of river co-learning arenas (RCAs) and explores their potential to strengthen innovative grassroots river initiatives, enliven river commons, regenerate river ecologies, and foster greater socio-ecological justice. The integrity of river systems has been threatened in profound ways over the last century. Pollution, damming, canalisation, and water grabbing are some examples of pressures threatening the entwined lifeworlds of human and non-human communities that depend on riverine systems.
View Article and Find Full Text PDFEffects of short time -30° head-down tilt on time perception.
Perception
January 2025
Hebei Normal University, China.
Exposure to microgravity induces abnormal experiences that may affect the perception of time. Head-down tilts (HDTs) are commonly used to investigate the effects of weightlessness. A -30° HDT is considered an appropriate model to simulate the acute phase of microgravity exposure.
View Article and Find Full Text PDFCausal inference with cross-temporal design.
Biometrics
January 2025
Department of Biostatistics, Brown University, Providence, RI 02903, United States.
When many participants in a randomized trial do not comply with their assigned intervention, the randomized encouragement design is a possible solution. In this design, the causal effects of the intervention can be estimated among participants who would have experienced the intervention if encouraged. For many policy interventions, encouragements cannot be randomized and investigators need to rely on observational data.
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