A new withanolide, talasteroid (), and a known steroid (), along with eight meroterpenoids (-), were obtained from the rice culture of the marine-derived fungus HBU-115. The structure of including its absolute configuration was determined by extensive 1 D and 2 D NMR spectroscopy, and single-crystal X-ray diffraction analysis. Compound represents the first withanolide featuring a 4-substituted 2,3-dimethyl-2-butenolide ring in the side chain. The isolated compounds were evaluated for their antimicrobial and antioxidant activities.
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http://dx.doi.org/10.1080/14786419.2022.2070747 | DOI Listing |
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