Chemoselective construction of naphthoxazoles (NapOx) a three-component annulation reaction enables proline selective labeling of peptides in solution or in solid-phase synthesis. The fluorogenic peptides possess low cytotoxicity, efficient cell membrane permeability and excellent bioimaging potential for biomedical applications.
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| http://dx.doi.org/10.1039/d2cc01268e | DOI Listing |
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