The 18 F-FDG PET images of dementia with Lewy bodies and posterior cortical atrophy, a visual-cognitive phenotype described in patients with Alzheimer disease, show occipital lobe hypometabolism with relative sparing of the primary visual cortex (PVC) generating the "occipital tunnel" sign proposed by Sawyer and Kuo in 2017, which is viewable on the medial sagittal projection. We believe that the saving of PVC compared with the lateral occipital cortex can be better appreciated by capturing the posterior projection of the PVC in a 3D stereotactic surface projection map, and we propose the name of "occipital pole" sign for this evidence.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/RLU.0000000000004136 | DOI Listing |
Eur J Neurol
February 2025
Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy.
Objective: Disorders of arousal (DoA) are characterized by an intermediate state between wakefulness and deep sleep, leading to incomplete awakenings from NREM sleep. Multimodal studies have shown subtle neurophysiologic alterations even during wakefulness in DoA. The aim of this study was to explore the brain functional connectivity in DoA and the metabolic profile of the anterior and posterior cingulate cortex, given its pivotal role in cognitive and emotional processing.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of Psychiatry, University of North Carolina at Chapel Hill, United States of America. Electronic address:
Background: Half of perimenopausal women experience depressive symptoms, including anhedonia. Anhedonia is associated with dysregulation of the frontostriatal circuit. Both the frontrostriatal circuit and depression may be regulated by the reproductive hormone estradiol (E2).
View Article and Find Full Text PDFBrain Struct Funct
January 2025
CHRIST (Deemed to be University), Bangalore, Karnataka, India.
In this investigation, we delve into the neural underpinnings of auditory processing of Sanskrit verse comprehension, an area not previously explored by neuroscientific research. Our study examines a diverse group of 44 bilingual individuals, including both proficient and non-proficient Sanskrit speakers, to uncover the intricate neural patterns involved in processing verses of this ancient language. Employing an integrated neuroimaging approach that combines functional connectivity-multivariate pattern analysis (fc-MVPA), voxel-based univariate analysis, seed-based connectivity analysis, and the use of sparse fMRI techniques to minimize the interference of scanner noise, we highlight the brain's adaptability and ability to integrate multiple types of information.
View Article and Find Full Text PDFNMR Biomed
January 2025
Support Centre for Advanced Neuroimaging, Institute for Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland.
Spin-lock (SL) pulses have been proposed to directly detect neuronal activity otherwise inaccessible through standard functional magnetic resonance imaging. However, the practical limits of this technique remain unexplored. Key challenges in SL-based detection include ultra-weak signal variations, sensitivity to magnetic field inhomogeneities, and potential contamination from blood oxygen level-dependent effects, all of which hinder the reliable isolation of neuronal signals.
View Article and Find Full Text PDFFront Integr Neurosci
September 2024
Hospital Israelita Albert Einstein, São Paulo, Brazil.
Background: This study aimed to investigate the neural mechanisms that differentiate mind-body practices from aerobic physical activities and elucidate their effects on cognition and healthy aging. We examined functional brain connectivity in older adults (age > 60) without pre-existing uncontrolled chronic diseases, comparing Tai Chi with Water Aerobics practitioners.
Methods: We conducted a cross-sectional, case-control fMRI study involving two strictly matched groups ( = 32) based on gender, age, education, and years of practice.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!