Purpose: Assess the impact the force-plate actometer, invented by Stephen C. Fowler, has had on behavioral neuroscience so far and what may be possible for future progress.
Methods: The web service Scopus was queried on April 28, 2021 for articles that cited the Journal of Neuroscience Methods paper titled "A force-plate actometer for quantitating rodent behaviors: illustrative data on locomotion, rotation, spatial patterning, stereotypies, and tremor" resulting in 134 articles. Articles were coded by the author for type (e.g., research, review, book chapter), phenomenon (e.g., stress, addiction), intervention (e.g., pharmacological), and measure (e.g., distance traveled, tremor).
Conclusions: Of the 134 citations, 116 were research articles, 10 were review articles, 7 were book chapters and one was an advertisement. The force-plate actometer has been used to study a variety of phenomena and its measurement capabilities were expanded. While primarily used for rats and mice, other species have been used.
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http://dx.doi.org/10.1016/j.brainresbull.2022.04.009 | DOI Listing |
J Neurosci Methods
March 2024
Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, USA. Electronic address:
Background: Self-grooming behavior in rodents serves as a valuable behavioral index for investigating stereotyped and perseverative responses. Most current grooming analyses rely on video observation, which lacks standardization, efficiency, and quantitative information about force. To address these limitations, we developed an automated paradigm to analyze grooming using a force-plate actometer.
View Article and Find Full Text PDFbioRxiv
July 2023
Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.
Background: Self-grooming behavior in rodents serves as a valuable model for investigating stereotyped and perseverative responses. Most current grooming analyses primarily rely on video observation, which lacks standardization, efficiency, and quantitative information about force. To address these limitations, we developed an automated paradigm to analyze grooming using a force-plate actometer.
View Article and Find Full Text PDFBrain Res Bull
August 2022
Potomac, MD, USA. Electronic address:
Tremor is an involuntary, rhythmic movement disorder. Despite its prevalence, the underlying pathophysiology remains poorly understood, and effective treatment options are limited. Animal models are essential in enhancing our understanding of the mechanisms of tremorogenesis and developing new therapeutic interventions.
View Article and Find Full Text PDFBrain Res Bull
July 2022
National Institute on Drug Abuse, 301 North Stonestreet Ave, Bethesda, MD 20892, USA. Electronic address:
Purpose: Assess the impact the force-plate actometer, invented by Stephen C. Fowler, has had on behavioral neuroscience so far and what may be possible for future progress.
Methods: The web service Scopus was queried on April 28, 2021 for articles that cited the Journal of Neuroscience Methods paper titled "A force-plate actometer for quantitating rodent behaviors: illustrative data on locomotion, rotation, spatial patterning, stereotypies, and tremor" resulting in 134 articles.
Brain Res Bull
April 2022
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, United States.
Evaluating and quantifying the many aspects of movement - from open-field locomotion and stepping patterns in rodent models to stride trajectory and postural sway in human patients - are key to understanding brain function. Various experimental approaches have been used in applying these lines of research to investigate the brain mechanisms underlying neurodegenerative disease. Although valuable, data on movement are often limited by the shortcomings inherent in the data collection process itself.
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