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Smartphone-based non-invasive detection of salivary uric acid based on the fluorescence quenching of gleditsia sinensis carbon dots.
Mikrochim Acta
January 2025
Guizhou Province, Qianzhi Mingguang Soaphorn Rice Processing Base, Zhijin County, Maochang Town, Bijie CityBijie City, 552103, China.
A smartphone-based non-invasive method was developed for salivary uric acid detection using Gleditsia Sinensis carbon dots (GS-CDs). The GS-CDs synthesized by the one-pot hydrothermal method emitted blue fluorescence at a maximum excitation wavelength of 350 nm and had good fluorescence stability in the presence of different ions, while showing selectivity to uric acid solution. The ability of uric acid (UA) to quench the fluorescent substances present in the GS-CDs, was confirmed through HPLC-FLD and LC-MS, FTIR and XPS.
View Article and Find Full Text PDFSaponins enhance the stability and cost-efficiency of human embryonic stem cell culture.
Cell Regen
January 2025
Department of Neurology, Zhongshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.
The cultivation and differentiation of human embryonic stem cells (hESCs) into organoids are crucial for advancing of new drug development and personalized cell therapies. Despite establishing of chemically defined hESC culture media over the past decade, these media's reliance on growth factors, which are costly and prone to degradation, poses a challenge for sustained and stable cell culture. Here, we introduce an hESC culture system(E6Bs) that facilitates the long-term, genetically stable expansion of hESCs, enabling cells to consistently sustain high levels of pluripotency markers, including NANOG, SOX2, TRA-1-60, and SSEA4, across extended periods.
View Article and Find Full Text PDFCellulose Elementary Fibrils as Deagglomerated Binder for High-Mass-Loading Lithium Battery Electrodes.
Nanomicro Lett
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Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-Ro, Seodaemun-Gu, Seoul, 03722, Republic of Korea.
Amidst the ever-growing interest in high-mass-loading Li battery electrodes, a persistent challenge has been the insufficient continuity of their ion/electron conduction pathways. Here, we propose cellulose elementary fibrils (CEFs) as a class of deagglomerated binder for high-mass-loading electrodes. Derived from natural wood, CEF represents the most fundamental unit of cellulose with nanoscale diameter.
View Article and Find Full Text PDFRobust bifunctionality towards hydrogen evolution and ethanol oxidation reactions catalyzed by six-element high-entropy alloys.
Chem Commun (Camb)
January 2025
Faculty of Materials Science and Chemistry, China University of Geosciences Wuhan, 388 Lumo RD, Wuhan, 430074, China.
FeCoNiIrPtPd/NCNT exhibits 3.4- and 1.6-fold higher levels of mass activity than does commercial Pt/C in the hydrogen evolution reaction (HER) and ethanol oxidation reaction (EOR), respectively.
View Article and Find Full Text PDFAdvances in the Release of Amide-Containing Molecules.
Chemistry
January 2025
University of Cambridge, Department of Chemistry, Lensfield Road, CB2 1EW, Cambridge, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
The ability to release a molecule from a larger construct in a controlled manner is of great importance to produce effective prodrugs, antibody-drug conjugates, and chemical probes. Amides are ubiquitous functional groups and yet methods to utilise them as molecular release handles are seldom reported. This concept article highlights the advances made in amide release strategies and how these approaches have been utilised.
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