AI Article Synopsis
- A study at the Grenoble-Alpes 32 university hospital examined the effectiveness and safety of dalbavancin in elderly patients, with 51% of the 65 subjects being classified as older adults.
- The majority of infections treated included bone and joint infections (52%), surgical site infections (31%), and infective endocarditis (8%).
- Clinical cure rates were high at 79% among elderly patients, with only 9% experiencing adverse events, indicating that dalbavancin is a promising treatment for complex infections in this population.
Article Abstract
We investigate dalbavancin efficiency and tolerance among elderly in Grenoble-Alpes 32 university hospital. Among the 65 patients who received dalbavancin, 51% (33) were considered as old. Patients presented mainly bones and joint infections (52%), surgical site infection 34 (31%), and infective endocarditis (IE) (8%). Clinical cure was confirmed for 79% of old 35 patients at 1, 3, and 6 months. Six adverse events (9%) were reported after 36 dalbavancin's administration, but each time in combination with other antibiotics. 37 Dalbavancin had a significant effectiveness and safety profile and represents a real 38 therapeutic option in the management of deep and complex infections of elderly patients.
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| http://dx.doi.org/10.1007/s10096-022-04427-2 | DOI Listing |
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