We describe an analytic method of the initial design of microscope objectives with a long working distance. The optical system of a microscope objective is composed of two thin optical elements and a frontal optical element from several thick lenses. The paper describes formulas that make it possible to calculate fundamental parameters of the objective, namely Seidel aberration coefficients, radii of curvature, refractive indices of individual lenses of the microscope objective, etc. The proposed method of calculation of the initial design parameters of the microscope objective, which is based on the theory of aberrations of the third order and chromatic aberrations of the first order, enables us to obtain a good starting design for further optimization using optical design software. The method of the design is presented in an example of the microscope objective with a long working distance.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/AO.455543 | DOI Listing |
J Rhinol
November 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Background And Objectives: Microplastics, which originate from the breakdown of larger plastic fragments or are intentionally produced for industrial applications, pose significant human and ecological risks through inhalation, ingestion, and dermal contact. Our study examined the release of microplastics during the preparation of homemade saline solutions, specifically when tearing open powder packets and mixing the powder with water.
Methods: We used commercially available polypropylene nasal irrigation bottles from the Korean market and collected six samples of nasal irrigation fluids.
Front Neurol
December 2024
Department of Radiology, Zigong First People's Hospital, Zigong, Sichuan, China.
Objectives: Understanding the microscopic pathophysiological mechanisms underlying acute ischemic stroke (AIS) is vital for facilitating early clinical diagnosis and intervention. In this study, we aimed to quantitatively assess brain iron changes in gray matter (GM) nuclei in patients with AIS via quantitative susceptibility mapping (QSM).
Methods: Thirty-four patients with AIS and thirty age-and sex-matched healthy controls (HCs) were included.
Biotechniques
January 2025
Biomedical Engineering, The University of Arizona, Tucson, AZ, USA.
Current dorsal skin flap window chambers with flat glass windows are compatible with optical coherence tomography (OCT) and multiphoton microscopy (MPM) imaging. However, light sheet fluorescence microscopy (LSFM) performs best with a cylindrical or spherical sample located between its two 90° objectives and when all sample materials have the same index of refraction (). A modified window chamber with a domed viewing window made from fluorinated ethylene propylene (FEP), with n similar to water and tissue, was designed.
View Article and Find Full Text PDFJ Otolaryngol Head Neck Surg
January 2025
Division of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals, University of Geneva, Geneva, Switzerland.
Background: A vestibular implant can partially restore vestibular function by providing motion information through implanted electrodes. During vestibular implantation, various obstructions of the semicircular canals, such as protein deposits, fibrosis, and ossification, can be encountered. The objective was to explore the relationship between preoperative imaging and intraoperative findings of semicircular canal obstruction and to develop surgical strategies for dealing with obstructions of the semicircular canal(s) in patients eligible for vestibular implantation.
View Article and Find Full Text PDFAnn Agric Environ Med
December 2024
Strategies and Programmess, State Institute Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health, Odessa, Ukraine.
Introduction And Objective: Elimination irrigation therapy has been proposed as a potential treatment for upper respiratory tract infections, particularly after the COVID-19 pandemic, due to its antiviral properties and mechanical cleansing effects. Additionally, a combination of mineral water with antibiotic therapy has shownto be effective in improving the course clinical infection and positively impact the immune system, potentially enhancing the normal state of microbiota state. The aim of the study is to investigate the influence of elimination-irrigation therapy using a combination of mineral water and ciprofloxacin on the interaction form of individual microbiota species of the upper respiratory tract mucous membrane.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!