Objectives: To describe the differences in clinical presentation and relative disease burden of congenital Zika syndrome (CZS)-associated microcephaly at 2 large hospitals in Salvador, Brazil that serve patients of different socioeconomic status (SES).
Methods: Clinical and serologic data were collected prospectively from pregnant women and their infants, who delivered at 2 study centers during the 2015-2016 Zika virus (ZIKV) epidemic in Salvador, Brazil.
Results: Pregnant women from Salvador, Brazil delivering in a low SES hospital had 3 times higher ZIKV exposure rate than women at a high SES hospital. However, different SES hospitals had similar prevalence of infants with CZS-associated microcephaly (10% vs 6%, p = 0.16) after controlling for ZIKV exposure in their mothers.
Conclusions: Our study supports the positive association between low SES, high maternal ZIKV exposure, and high rates of CZS-associated microcephaly.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119857 | PMC |
http://dx.doi.org/10.1016/j.ijid.2022.04.030 | DOI Listing |
Trop Anim Health Prod
December 2024
Department of Animal Science, Federal University of Campina Grande, Patos, Paraíba, 58708110, Brazil.
This study aimed to develop, characterize, and validate an encapsulant based on beeswax (BW) for rumen-protected fat (RPF) using the melting emulsification technique. Buriti oil (BO) was used as the core material, and BW was used as the encapsulating material at three different proportions of BW:BO (9:1, 4:1, and 2:1 g/g ratio respectively). RPF microspheres (BWBO9:1, BWBO4:1, and BWBO2:1) were characterized and tested in six 3-year-old castrated male Santa Ines sheep (average body weight of 56.
View Article and Find Full Text PDFLancet Microbe
December 2024
Amsterdam University Medical Centres, Amsterdam, Netherlands; Department of Global Health and Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.
Background: Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the protection against disease would accelerate tuberculosis vaccine development. We aimed to assess whether the effectiveness of the Bacillus Calmette-Guérin (BCG) vaccine for prevention of Mycobacterium tuberculosis infection was consistent with that for prevention of tuberculosis disease.
View Article and Find Full Text PDFInt J Sports Physiol Perform
December 2024
Department of Human Movement Sciences, Federal University of São Paulo, São Paulo, Brazil.
Purpose: We tested the differences in maximum strength and various parameters of sprint performance between youth backs and forwards. Additionally, we examined the associations among various strength-sprint measures, as well as between unresisted and heavy resisted sprints.
Methods: Thirty-two youth rugby players were assessed at the beginning of the season with the following tests: unresisted and resisted (50% body mass) 30-m sprints and 1-repetition maximum (1RM) in the squat exercise.
Vaccine
December 2024
Health Science Research Laboratory, Federal University of Grande Dourados, Dourados, Mato Grosso, do Sul, Brazil.. Electronic address:
J Acad Consult Liaison Psychiatry
December 2024
Bahiana School of Medicine and Public Health, Salvador, BA Brazil.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!