MMN and P3a elicited by a novelty paradigm in healthy controls: An investigation of sex differences.

Neurosci Lett

Department of Psychology, Dalhousie University, Halifax, NS, Canada; Department of Psychology, Saint Mary's University, Halifax, NS, Canada; Department of Psychology, Mount Saint Vincent University, Halifax, NS, Canada. Electronic address:

Published: June 2022

AI Article Synopsis

  • The study focuses on two brain waveforms, MMN and P3a, which are indicators of how we detect changes in sounds.
  • MMN reflects difficulties in auditory change detection, while P3a relates to the conscious evaluation of those sounds.
  • The researchers found no significant sex differences in these waveforms among healthy individuals, contributing valuable information to the existing research on how biological sex might influence auditory processing.

Article Abstract

The mismatch negativity (MMN) and P3a waveforms are both markers of auditory change detection. MMN indicates deficits in performing auditory change-detection tasks, while the P3a reflects the evaluative and conscious aspect of orienting to the sound. Understanding the role biological sex has concerning these waveforms would provide insight into overall brain-based differences, but whether sex differences exist to such a degree that it can moderate the effect of auditory change detection is not certain. Thus, the purpose of this study was to examine potential sex differences in MMN and P3a elicited by a novelty paradigm in a healthy population. The results showed no significant differences between males and females. This study proves to be useful by adding to the limited literature on the topic and by providing a foundation of knowledge regarding sex differences in auditory change detection mechanisms within the population.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2022.136654DOI Listing

Publication Analysis

Top Keywords

sex differences
16
mmn p3a
12
auditory change
12
change detection
12
p3a elicited
8
elicited novelty
8
novelty paradigm
8
paradigm healthy
8
differences
6
sex
5

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!