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Variable impacts of land-based climate mitigation on habitat area for vertebrate diversity.
Science
January 2025
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Pathways to achieving net zero carbon emissions commonly involve deploying reforestation, afforestation, and bioenergy crops across millions of hectares of land. It is often assumed that by helping to mitigate climate change, these strategies indirectly benefit biodiversity. Here, we modeled the climate and habitat requirements of 14,234 vertebrate species and show that the impact of these strategies on species' habitat area tends not to arise through climate mitigation, but rather through habitat conversion.
View Article and Find Full Text PDFVenetoclax and azacitidine in combination with homoharringtonine, cytarabine, and aclarubicin for salvage therapy of relapsed/refractory T cell acute lymphoblastic leukemia.
Int J Hematol
January 2025
Department of Hematology, The 920th Hospital of Joint Logistics Support Force, No.212, Da Guan Road, Xishan District, Kunming, 650100, Yunnan, China.
Background: The treatment of relapsed/refractory T cell acute lymphoblastic leukemia (R/R T-ALL) is a significant challenge in hematologic oncology, and no standard salvage treatment plan exists. Both Chinese and international clinical guidelines recommend combination chemotherapy including venetoclax.
Methods: Efficacy and safety of venetoclax, azacitidine, homoharringtonine, cytarabine, and aclarubicin (VA-HAA) combination therapy were retrospectively analyzed in 3 patients with R/R T-ALL at the Department of Hematology, 920th Hospital of the Joint Logistics Support Force, Chinese People's Liberation Army.
Ni Single Atoms/FeN Nanoparticles Supported by N-Doped Carbon Hollow Nanododecahedras with Nanotubes on the Surface for Efficient Electro-Reduction of CO to CO.
Small
January 2025
College of Materials Science and Engineering, Sichuan University, Chengdu, 610065, China.
The transition metal single atoms (SAs)-based catalysts with M-N coordination environment have shown excellent performance in electrocatalytic reduction of CO, and they have received extensive attention in recent years. However, the presence of SAs makes it very difficult to efficiently improve the coordination environment. In this paper, a method of direct high-temperature pyrolysis carbonization of ZIF-8 adsorbed with Ni and Fe ions is reported for the synthesis of Ni SAs and FeN nanoparticles (NPs) supported by the N-doped carbon (NC) hollow nanododecahedras (HNDs) with nanotubes (NTs) on the surface (Ni SAs/FeN NPs@NC-HNDs-NTs).
View Article and Find Full Text PDFReduced autoimmunity associated with deletion of host CD73.
Immunohorizons
January 2025
Department of Pediatrics, Division of Gastroenterology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
CD73 is ubiquitously expressed and regulates critical functions across multiple organ systems. The sequential actions of CD39 and CD73 accomplish the conversion of adenosine triphosphate to adenosine and shift the adenosine triphosphate-driven proinflammatory immune cell milieu toward an anti-inflammatory state. This immunological switch is a major mechanism by which regulatory T (Treg) cells control inflammation.
View Article and Find Full Text PDFA Fish-Gill-Inspired Biomimetic Multiscale-Ordered Hydrogel-Based Solar Water Evaporator for Highly Efficient Salt-Rejecting Seawater Desalination.
ACS Appl Mater Interfaces
January 2025
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China.
Solar energy-driven steam generation is a renewable, energy-efficient technology that can alleviate the global clean water shortage through seawater desalination. However, the contradiction between resistance to salinity accretion and maintaining high water evaporation properties remains a challenging bottleneck. Herein, we have developed a biomimetic multiscale-ordered hydrogel-based solar water evaporator for efficient seawater desalination.
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