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http://dx.doi.org/10.1038/s41437-022-00534-0 | DOI Listing |
PLoS Comput Biol
January 2025
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
The "similarity of dissimilarities" is an emerging paradigm in biomedical science with significant implications for protein function prediction, machine learning (ML), and personalized medicine. In protein function prediction, recognizing dissimilarities alongside similarities provides a more detailed understanding of evolutionary processes, allowing for a deeper exploration of regions that influence biological functionality. For ML models, incorporating dissimilarity measures helps avoid misleading results caused by highly correlated or similar data, addressing confounding issues like the Doppelgänger Effect.
View Article and Find Full Text PDFPLoS One
January 2025
College of Geography and Environmental Science, Guizhou Normal University, Guiyang, China.
It is significant to research the ecological risk of land use landscape to promote ecological conservation and restoration. The characteristics of land use dynamic change in Baili Rhododendron National Forest Park were analyzed based on GlobeLand30 data for three periods in 2000, 2010 and 2020. With the support of the landscape ecological risk evaluation model and spatial analysis methods, the features of spatial and temporal differentiation of ecological risk and its spatial correlation in the study area were evaluated.
View Article and Find Full Text PDFDatabase (Oxford)
January 2025
Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Amidst the global challenge of extreme poverty, the livestock sector can significantly contribute to global sustainable development goals by enhancing resilience, smallholder productivity, and market participation. The Indian livestock sector is one of the largest in the world with a total livestock population of 535.82 million, ∼10.
View Article and Find Full Text PDFVet Sci
December 2024
Guangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
The global epidemic of bovine coronavirus (BCoV) has caused enormous economic losses. The characterisation and genetic composition of endemic strains in Southwest China remain elusive. This study aimed to fill this gap by isolating three BCoV strains from this region and sequencing their whole genomes.
View Article and Find Full Text PDFJ Fungi (Basel)
January 2025
Institute for Medicinal Plants, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
is an important fungus with medicinal properties and a significant role in lignocellulose degradation. In this study, we constructed a high-quality chromosome-level genome of using Illumina, PacBio HiFi, and Hi-C sequencing technologies. The assembled genome is 47.
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