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Validated LC-MS/MS methodology for the quantification of CBD, trace level THCA and UK controlled cannabinoids (Δ-THC, Δ-THC, CBN and THCV) in food samples.
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LGC, Queens Road, Teddington, TW11 0LY, UK.
Products containing cannabidiol (CBD) have become increasingly popular due to consumer-perceived benefits of improving health and well-being. More specifically in the United Kingdom (UK), CBD food products are categorised as . For these products to remain on the market, they must have authorisation from the Food Standards Agency on the basis that they are safe, correctly labelled, and do not contain substances classified under controlled drugs legislation in accordance with any existing or future Home Office guidance.
View Article and Find Full Text PDFOn the Effect of the Patient Table on Attenuation in Myocardial Perfusion Imaging SPECT.
EJNMMI Phys
January 2025
Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, University Hospital (Ruhr University Bochum), Medical Faculty OWL (Bielefeld University), Bad Oeynhausen, Germany.
Background: The topic of the effect of the patient table on attenuation in myocardial perfusion imaging (MPI) SPECT is gaining new relevance due to deep learning methods. Existing studies on this effect are old, rare and only consider phantom measurements, not patient studies. This study investigates the effect of the patient table on attenuation based on the difference between reconstructions of phantom scans and polar maps of patient studies.
View Article and Find Full Text PDFSafety, Tolerability, and Pharmacokinetics of a Novel Anti-obesity Agent, S-309309, in Healthy Adults with or Without Obesity.
Clin Drug Investig
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Medical Science Department, Shionogi & Co., Ltd., Osaka, Japan.
Background: Anti-obesity medications are recommended for patients who do not achieve and maintain weight loss despite lifestyle interventions. S-309309 is a novel oral inhibitor of monoacylglycerol O-acyltransferase 2 being developed as a treatment for obesity.
Objective: The objective of the study was to investigate the safety, clinical pharmacology, pharmacokinetics and pharmacodynamic biomarker of S-309309.
Correction: Curcumol Attenuates Portal Hypertension and Collateral Shunting Via Inhibition of Extrahepatic Angiogenesis in Cirrhotic Rats.
Biochem Genet
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Development of Emergency, The First Affiliated Hospital of Guangxi University of Chinese Medicine, No.28 Wangyuan Road, Qingxiu District, Nanning, 530000, China.
Hierarchical MoS@NiFeCo-Mo(doped)-Layered Double Hydroxide Heterostructures as Efficient Alkaline Water Splitting (Photo)Electro-catalysts.
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Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box 35, Jyväskylä, FI-40014, Finland.
Designing cost-effective electrocatalysts with fast reaction kinetics and high stability is an outstanding challenge in green hydrogen generation through overall water splitting (OWS). Layered double hydroxide (LDH) heterostructure materials are promising candidates to catalyze both oxygen evolution reaction (OER) and hydrogen evolution reaction (HER), the two OWS half-cell reactions. This work develops a facile hydrothermal route to synthesiz hierarchical heterostructure MoS@NiFeCo-LDH and MoS@NiFeCo-Mo(doped)-LDH electrocatalysts, which exhibit extremely good OER and HER performance as witnessed by their low IR-corrected overpotentials of 156 and 61 mV with at a current density of 10 mA cm under light assistance.
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