AI Article Synopsis
- * A rare side effect known as paradoxical excitation can occur, where patients may experience increased agitation or excitement instead of the intended calming effects.
- * Failure to recognize and manage this adverse effect can negatively impact a patient's treatment progress in a hospital setting.
Article Abstract
Benzodiazepines are commonly used medications which are clinically useful towards the treatment of alcohol withdrawal, seizures, anxiety disorders, among other indications. Benzodiazepine use is also known to cause the rare phenomenon of paradoxical excitation whose mechanism has many postulated theories. We report this rare presentation of paradoxical excitation with the use of lorazepam in a 50-year-old male being treated for alcohol withdrawal. We also review the underlying pathophysiology, pharmacology, and current literature as it relates to this excitation. An inability to recognize this adverse effect and to appropriately withhold the agent may adversely affect a patient's course of treatment in the inpatient setting.
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| http://dx.doi.org/10.1177/08971900221097182 | DOI Listing |
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