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Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study.
JAMA Netw Open
January 2025
Alzheimer Center Limburg, Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Importance: Baseline cerebral microbleeds (CMBs) and APOE ε4 allele copy number are important risk factors for amyloid-related imaging abnormalities in patients with Alzheimer disease (AD) receiving therapies to lower amyloid-β plaque levels.
Objective: To provide prevalence estimates of any, no more than 4, or fewer than 2 CMBs in association with amyloid status, APOE ε4 copy number, and age.
Design, Setting, And Participants: This cross-sectional study used data included in the Amyloid Biomarker Study data pooling initiative (January 1, 2012, to the present [data collection is ongoing]).
Depressive Symptoms and Amyloid Pathology.
JAMA Psychiatry
January 2025
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Importance: Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive symptoms and amyloid pathology.
View Article and Find Full Text PDFThe publication fate of abstracts awarded prizes at European Society of Paediatric Radiology annual scientific meetings.
Pediatr Radiol
January 2025
School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Background: The European Society of Paediatric Radiology (ESPR) awards prizes for outstanding work presented at their annual scientific meetings. The proportion of ESPR prize-winning abstracts to journal publications is not known. Contextualising abstract-to-publication proportions by evaluating publication experience can yield valuable insights and actionable outcomes to support researchers in overcoming barriers to journal publication.
View Article and Find Full Text PDFPosition statement on longitudinal cracks and fractures of teeth.
Int Endod J
January 2025
Centre for Oral, Clinical & Translational Sciences, King's College London, London, UK.
This position statement is a consensus view of an expert committee convened by the European Society of Endodontology (ESE). The statement is based on current clinical and scientific evidence as well as the collective reflective practice of the committee. The aim is to provide clinicians with evidence-based, authoritative information on the aetiology, clinical presentation, and management of cracks and fractures that typically manifest along the long axis of the crown and/or root.
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