AI Article Synopsis

  • Oxidative stress and obesity are major contributors to metabolic syndrome, making the search for effective treatments important.
  • A study focused on the hydro-ethanolic extract of an edible insect, identifying 60 bioactive components with high antioxidant and pancreatic lipase inhibitory activities.
  • Major polyphenols like salicylic acid and gallic acid were identified, showing potential for the extract to serve as a nutraceutical for reducing oxidative stress and managing obesity.

Article Abstract

Oxidative stress and obesity are critical risk factors for metabolic syndrome. The consumption of functional food ingredients can a viable strategy to alleviate oxidative stress and obesity. In this study, the hydro-ethanolic extract of the edible insect was prepared and its bioactive components were characterized. The total polyphenol contents, total flavonoid contents, antioxidant and pancreatic lipase (PL) inhibitory activities of the extract were determined . In total, 60 bioactive components were tentatively identified in the extract. Polyphenols and fatty acids were further quantified using LC-MS and GC-MS, respectively. extract possessed excellent antioxidant and PL inhibition activities. Salicylic acid, gallic acid, liquiritigenin, and naringenin, which were the major polyphenols in the extract, interacted with PL through hydrogen bonding, hydrophilic or hydrophobic and pi-cation interactions. Thus, extract can be used as a nutraceutical to alleviate oxidative stress-induced disease and manage obesity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021923PMC
http://dx.doi.org/10.3389/fnut.2022.860174DOI Listing

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