Background: Mechanical debridement of periodontal pockets remains the mainstay of therapy in all forms of periodontitis. There is 47% greater reduction in plaque amount when sodium hypochlorite (NaOCl) is used as an adjunct when compared with water rinsing. The aim of this study was to evaluate the effects of 0.05% NaOCl and 0.12% chlorhexidine gluconate twice daily rinse on periodontal parameters and gingival crevicular fluid (GCF) HSV1 and CMV levels in chronic periodontitis.

Methods: Patients assigned to group A were prescribed 0.05% NaOCl mouthwash for twice daily rinse. Patients in group B were prescribed 0.12% chlorhexidine gluconate mouthwash to be used twice daily. Evaluation of periodontal parameters was done at baseline and after six months following therapy. GCF HSV1 and CMV levels were evaluated using a polymerase chain reaction.

Results: A statistically significant difference was noted in the improvement in periodontal parameters between both groups, when evaluated six months following therapy with greater reduction in group A vis-a-vis group B.

Conclusion: NaOCl when prescribed as a twice daily mouthwash can be recommended as a part of the home care regime in patients with chronic periodontitis. It is more cost-effective, easily available and can be beneficial to the troops in difficult terrains and extremes of climates, where oral healthcare facilities are not easily accessible.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023539PMC
http://dx.doi.org/10.1016/j.mjafi.2020.08.002DOI Listing

Publication Analysis

Top Keywords

periodontal parameters
16
012% chlorhexidine
12
chlorhexidine gluconate
12
daily rinse
12
cmv levels
12
effects 005%
8
sodium hypochlorite
8
gluconate daily
8
rinse periodontal
8
parameters gingival
8

Similar Publications

Objective: This study aimed to evaluate the trabecular microarchitecture in the interdental region of panoramic radiographs from periodontally healthy individuals and those with stage III/IV periodontitis using fractal analysis (FA), while also assessing the relationship between clinical periodontal parameters and FA outcomes.

Study Design: Clinical and radiographic records of 20 periodontally healthy individuals and 19 individuals with stage III/IV periodontitis were included. Clinical measurements including the plaque score, bleeding on probing, probing pocket depth, and clinical attachment level were recorded.

View Article and Find Full Text PDF

Background: Treatment of gingival recessions through surgical approaches is a common periodontal intervention. There is a rise in using biologics in root coverage procedures. As it has been shown that hyaluronic acid (HA) promotes wound healing, this review aimed to assess its efficacy in the treatment of gingival recessions.

View Article and Find Full Text PDF

Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.

J Periodontal Res

January 2025

Division of Periodontology, Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.

Aim: To assess tissue perfusion changes and wound healing biomarker levels after root coverage procedures with coronally advanced flap in combination with the cross-linked xenogeneic collagen matrix (CCMX), loaded either with a placebo or recombinant human platelet-derived growth factor-BB (rhPDGF).

Methods: This study was designed as a secondary analysis from a previously published clinical trial, and it assessed the tissue perfusion changes over 6 months around multiple gingival recession defects, treated with either with CCMX alone (control) or with CCMX + rhPDGF (test). High frequency Doppler ultrasonography (HFUS) scans were obtained at sites of interest at baseline, 2 weeks, 3 months, and 6 months after surgery.

View Article and Find Full Text PDF

Aim: To evaluate the clinical effectiveness of ozonated sunflower oil (Oz) as an adjunctive of non-surgical periodontal therapy in patients with type 2 diabetes mellitus (DM2), on fibroblast cell viability and migration and the effectiveness of Oz on a Candida albicans (C. albicans) culture.

Methodology: In total, 32 sites in 16 DM2 with moderate to advanced periodontal disease with periodontal pocket depths ≥5mm were selected.

View Article and Find Full Text PDF

Conventional periodontal probing versus salivary biomarkers in diagnosis and evaluation of chronic periodontitis in type 2 diabetes mellitus.

Minerva Dent Oral Sci

January 2025

Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India -

Chronic periodontitis is a prevalent inflammatory condition that affects both the oral health and systemic well-being of individuals, particularly those with type 2 diabetes mellitus (T2DM). Accurate diagnosis and evaluation of periodontal status are crucial for effective management of the disease. This narrative review aimed to compare the diagnostic and evaluative capabilities of conventional periodontal probing and salivary biomarkers in chronic periodontitis among individuals with T2DM.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!