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| http://dx.doi.org/10.3389/fpsyt.2022.881245 | DOI Listing |
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A tribute to Laszlo Zaborszky: pioneering discoveries in the basal forebrain and inspiring generations of neuroscientists.
Brain Struct Funct
December 2024
School of Medicine, Department of Neuropharmacology, Western Sydney University, Locked Bag 1797, Penrith, NSW, 2751, Australia.
This editorial celebrates the 80th birthday of Distinguished Professor Laszlo Zaborszky, co-founder of Brain Structure and Function, and reflects on his monumental contributions to neuroscience, particularly his pioneering work on the cholinergic basal forebrain. Professor Zaborszky's research has reshaped our understanding of this brain region's organization and function, uncovering its critical role in cognitive processes such as learning, memory, and attention. His findings have challenged longstanding assumptions, demonstrating that the cholinergic projections to the cortex are highly organized, with implications for neurodegenerative diseases like Alzheimer's.
View Article and Find Full Text PDFAssociation of unplanned extubations and neurodevelopmental outcomes in very low birthweight infants.
J Perinatol
December 2024
Department of Pediatrics, Division of Neonatology, Vanderbilt University Medical Center, Nashville, TN, USA.
Exposure therapy consortium: Outcomes of the proof-of-principle study.
J Anxiety Disord
December 2024
Institut für Psychologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
Background: This paper reports on the outcomes of a proof-of-principle study for the Exposure Therapy Consortium, a global network of researchers and clinicians who work to improve the effectiveness and uptake of exposure therapy. The study aimed to test the feasibility of the consortium's big-team science approach and test the hypothesis that adding post-exposure processing focused on enhancing threat reappraisal would enhance the efficacy of a one-session large-group interoceptive exposure therapy protocol for reducing anxiety sensitivity.
Methods: The study involved a multi-site cluster-randomized controlled trial comparing exposure with post-processing (ENHANCED), exposure without post-processing (STANDARD), and a stress management intervention (CONTROL) in students with elevated anxiety sensitivity.
Predictive biosignatures for hospitalization in patients with virologically confirmed COVID-19.
J Chin Med Assoc
December 2024
Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Background: COVID-19, caused by the SARS-CoV-2 virus, presents with varying severity among individuals. Both viral and host factors can influence the severity of acute and chronic COVID-19, with chronic COVID-19 commonly referred to as long COVID. SARS-CoV-2 infection can be properly diagnosed by performing real-time reverse transcription PCR analysis of nasal swab samples.
View Article and Find Full Text PDFAddressing the role of surgery in brain tumour trials: A report from the neurosurgery committee of the EORTC brain tumour group.
Eur J Cancer
December 2024
Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.
The Brain Tumor Group (BTG) of the European Organization for Research and Treatment of Cancer (EORTC) conducts academic clinical trials and translational research to improve clinical management of patients with primary and secondary brain tumors. The EORTC BTG has traditionally played an important role in providing evidence and thus advancing the field, albeit with a main focus on radiotherapy and pharmacotherapy in gliomas. Although examples of well-designed neuro-oncological surgical trials can be found, evidence in surgical neuro-oncology predominantly includes data from uncontrolled prospective series or retrospective cohorts.
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