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Efficacy of Therapeutic Hypothermia During Transport of Newborns With Perinatal Hypoxic-Ischaemic Encephalopathy: Experience From Newborn and Paediatric Transport Service, New South Wales.
J Paediatr Child Health
December 2024
Newborn and Paediatric Emergency Transport Service, Bankstown, New South Wales, Australia.
Aim: To examine the efficacy of current non-servo-based cooling methods used by NETS NSW in treating hypoxic ischaemic encephalopathy (HIE) with therapeutic hypothermia (TH) in neonatal retrieval.
Methods: A retrospective observational study of infants treated with TH for HIE retrieved by NETS NSW from January 2017 to June 2020 inclusive. Primary outcomes were the proportion of neonates achieving TH within 6 h of life and maintaining temperature in a therapeutic range.
Association of community characteristics as measured by social deprivation index score with prenatal care and obstetrical outcomes.
Am J Perinatol
December 2024
Department of Obstetrics & Gynecology, Baylor College of Medicine, Houston, United States.
Objective We aimed to determine the relationships between socioeconomic disadvantage, as measured by the Social Deprivation Index (SDI), and prenatal care (PNC) utilization, obstetrical outcomes, and neonatal complications. Study Design All spontaneously-conceived singleton deliveries of nulliparous gravidae with residence zip code available (n= 4,786) were identified in a population-based database. Deliveries were assigned SDI scores based on preconception zip code.
View Article and Find Full Text PDFFunctional characterization and mechanism of the multidrug resistance transport potein YoeA in Bacillus subtilis.
Int J Biol Macromol
December 2024
Key Laboratory of Food Processing and Quality Control, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210000, PR China. Electronic address:
Transport proteins are essential for bacterial resistance to antibiotics and toxins, but their mechanisms remain poorly understood in Bacillus subtilis. In the present study, overexpression of yoeA enhanced resistance to various antibiotics, with its expression induced by these antibiotics, especially penicillin and plipastatin. The ΔyoeA strain exhibited significant growth inhibition at 100 μg/mL of plipastatin, while as high as 10,000 μg/mL of iturin/surfactin are required to achieve comparable inhibition, suggesting a higher sensitivity of ΔyoeA to plipastatin.
View Article and Find Full Text PDFEngineering CO-Ultraselective Membranes: Molecularly Tailored Low-Crystallinity Polyvinylamine-PEGDGE Networks.
ACS Appl Mater Interfaces
December 2024
Department of Chemical Engineering, Guangdong Technion - Israel Institute of Technology, 241 Daxue Road, Shantou, Guangdong 515063, China.
Facilitated transport membranes (FTMs) with an ultraselective layer prepared from amine-rich polyvinylamine (PVAm)/2-(1-piperazinyl)ethylamine salt of sarcosine (PZEA-Sar) (denoted by PM) and an amorphous dendritic cross-linked network of PVAm-functionalized poly(ethylene glycol)diglycidyl ether (PEGDGE) (named PP) were designed for CO separations. The developed membranes expedited CO transport over N through the synergistic effect from the induced CO-philic ethylene oxide groups and highly hydrophilic and polar hydroxyl groups together with the low-crystallinity PP networks, which offer a high diffusion rate for CO-amine complexes through the membrane and stabilize small molecular mobile carriers via hydrogen bonding. The best (PM/PP-10)/polysulfone (PSf) composite membranes achieved a superior CO/N selectivity of 230 (4.
View Article and Find Full Text PDFThe bulk photovoltaic effect (BPVE) and its artificial variant generate photocurrent under zero external bias in non-centrosymmetric systems, particularly in on-chip miniaturized metasurface-based photodetectors. Despite significant advancements, enhancing the efficiency of local photocurrent collection remains a challenge, often impeded by non-uniform flow fields in graphene caused by nanoantenna contacts, which lead to carrier transport losses. In this study, we conducted a comprehensive investigation into the regulation of local photocurrent collection in zero-bias optoelectronic metasurface-based photodetectors and explored the impact of nanoantenna array configurations on photocurrent efficiency.
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