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Comparison of estimated glomerular filtration rate using five equations to predict acute kidney injury following hip fracture surgery.
Orthop Traumatol Surg Res
December 2024
From the Department of Orthopaedic Surgery, Rush University, Chicago, IL, USA; From the Department of Orthopaedic Surgery, University of California San Francisco, University Orthopaedic Associates, Fresno, CA, USA.
Background: Decreased estimated glomerular filtration rate (eGFR) is associated with acute kidney injury (AKI) following hip fracture surgery. Delaying surgery for preoperative treatment of comorbidities is controversial in this patient population. The purpose of this study was 1) to assess differences in demographics and comorbidities between AKI and non-AKI groups, 2) to analyze equations used in calculating eGFR, and 3) to identify the equation which best predicts the development of AKI following hip fracture surgery.
View Article and Find Full Text PDFKidney function assessment for eligibility in clinical cancer trials - Data from the European Organisation for Research and Treatment of Cancer.
Eur J Cancer
October 2024
Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:
Purpose: There is no consensus on how to estimate kidney function for the assessment of eligibility in clinical cancer trials.
Patients And Methods: We recalculated the creatinine clearance (CrCl)/glomerular filtration rate (GFR) at baseline in a total of 1768 patients enrolled in twelve clinical trials using the Cockcroft-Gault (CG), Modification of Diet in Renal Disease (MDRD), 2021 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI 2021) and European Kidney Function Consortium (EKFC) formulas. Patients were classified as having renal impairment (RI; CrCl/GFR <60 mL/min) or no renal impairment (NRI; CrCl/GFR ≥60 mL/min) with each of the four formulas, respectively.
Evaluation of Six eGFR Equations in Predicting Acute Kidney Injury in Patients after Off-Pump Coronary Artery Bypass Grafting: A Case Control Study.
Rev Cardiovasc Med
April 2024
Department of Cardiac Surgical Care Unit, Affiliated Hospital of Qingdao University, 266003 Qingdao, Shandong, China.
Background: There are six widely used equations to calculate the estimated glomerular filtration rate (eGFR) of patients. We aimed to assess the predictive power of preoperative eGFR calculated by these equations for the occurrence of postoperative acute kidney injury (AKI).
Methods: Patients who underwent isolated coronary surgery from January 2016 to January 2021 were continuously enrolled.
Cisplatin eligibility in the neoadjuvant setting of patients with muscle-invasive bladder cancer undergoing radical cystectomy.
Oncologist
November 2024
Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam 1006, The Netherlands.
Article Synopsis
- The study investigates how well different eGFR formulas correlate with actual creatinine clearance (CrCI) measurements in patients with muscle-invasive bladder cancer (MIBC) undergoing cisplatin treatment.
- Conducted over a decade, the analysis found that while various eGFR calculations produced similar rates of cisplatin-ineligibility, they consistently underestimated actual kidney function as measured by CrCI.
- The research highlights that many patients previously classified as cisplatin-ineligible based on eGFR may actually be eligible when considering direct CrCI measurements, especially those with calculated eGFR values in the 40-59 mL/min range.
Evaluation of the clinical value of 10 estimating glomerular filtration rate equations and construction of a prediction model for kidney damage in adults from central China.
Front Mol Biosci
June 2024
Department of Nephrology, Anhui Medical University, Fuyang People's Hospital of Anhui Medical University, Fuyang, Anhui, China.
Objectives: This study aimed to evaluate 10 estimating glomerular filtration rate (eGFR) equations in central China population and construct a diagnostic prediction model for assessing the kidney damage severity.
Methods: The concordance of 10 eGFR equations was investigated in healthy individuals from central China, and their clinical effectiveness in diagnosing kidney injury was evaluated. Subsequently, relevant clinical indicators were selected to develop a clinical prediction model for kidney damage.
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