Introduction: Several autografts are available to reconstruct the posterior cruciate ligament (PCL).
Source Of Data: Current scientific literature published in PubMed, Google scholar, Embase and Scopus.
Areas Of Agreement: Hamstring, bone-patellar tendon-bone (BPTB), quadriceps and peroneus longus (PLT) are the most common tendon autografts used for primary isolated PCL reconstruction.
Areas Of Controversy: The optimal tendon source for PCL reconstruction remains nevertheless debated. Identifying the most suitable tendon autograft could assist the surgeon during primary PCL reconstruction.
Growing Points: The present study compared the outcome of PCL reconstruction using hamstring, BPTB, quadriceps and PLT autografts. The focus was on patient-reported outcome measures (PROMs), joint laxity, range of motion and complications.
Areas Timely For Developing Research: All autografts are viable options for PCL reconstruction, with BTB and hamstring autografts demonstrating superior PROMs. However, further clinical investigations are required to determine the ideal autograft construct.
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http://dx.doi.org/10.1093/bmb/ldac010 | DOI Listing |
Front Bioeng Biotechnol
January 2025
Department of Orthopaedics, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical Universit, Guangzhou, China.
Objective: The aim of this study is to assess the kinematic changes in the knee joint during walking in patients with isolated PCL-deficiency (PCLD) to determine the presence of walking-related joint instability (mechanical instability-abnormal displacement form structural damage). Additionally, the study seeks to provide biomechanical insights into the observed differences between subjective and objective assessments.
Methods: 35 healthy volunteers and 27 patients with isolated PCLD (both involved and uninvolved sides) were included in the study.
J Biomed Mater Res A
January 2025
Marquette University School of Dentistry, Milwaukee, Wisconsin, USA.
In this study, a new hybrid nanoparticle composed of magnesium hydroxide and copper oxide (Mg(OH)/CuO) with an optimized ratio of magnesium (Mg) to copper (Cu) was designed and incorporated into a 3D-printed scaffold made of polycaprolactone (PCL) and gelatin. These hybrid nanostructures (MCNs) were prepared using a green, solvent-free method. Their topography, surface morphology, and structural properties were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS).
View Article and Find Full Text PDFJ Vis Exp
December 2024
Department of Pharmacology, School of Medicine, Ajou University; 3D Immune System Imaging Core Center, Ajou University;
Technical hurdles in a culture of epithelial cells include dedifferentiation and loss of function. Biomimetic three-dimensional (3D) cell culture methods can enhance cell culture efficiency. This study introduces an advanced two-layered culture system intended to cultivate epithelial cells as tissue-like layers with the culture of fibroblasts within a 3D environment.
View Article and Find Full Text PDFBiomater Adv
January 2025
Department of Chemistry, Materials and Chemical Engineering G. Natta, Politecnico di Milano, Piazza Leonardo Da Vinci 32, Milan, Italy; Local Unit Politecnico di Milano, Milan, Italy. Electronic address:
Microtia, along with trauma, represents one of the main causes of external ear malformation. Different clinical techniques were developed for the reconstruction of the auricle, but they all have some drawbacks. This work is focused on the development of an innovative 3D porous scaffold, printed by Fused Deposition Modelling (FDM) and based on laser-scanned images of the healthy contralateral ear of the patient.
View Article and Find Full Text PDFMil Med
January 2025
Musculoskeletal Department, Naval Health Clinic Annapolis/United States Naval Academy, Annapolis, MD 21402, USA.
Introduction: Acute anterior cruciate ligament (ACL) injuries can be disabling because of prolonged rehabilitation process following surgical reconstructions. Rates of ACL injuries among military service members are close to 10 times greater than the general civilian population, likely because of the operation tempo and the unique physical requirements. Studies debated functional testing requirements for return to sports, but no study investigated the impact of functional training and re-injury rates following ACL reconstruction and their association with functional testing outcomes and time to return to full duty in United States Naval Academy (USNA) Midshipmen.
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