AI Article Synopsis

  • The study investigates whether individuals with self-reported digestive intolerance to dairy have compromised milk protein digestion.
  • Adult women (40) were classified into three groups based on their tolerance to dairy and tested with different milk types to measure their plasma amino acid levels post-ingestion.
  • Results showed that while all participants generally saw an increase in amino acids after consuming milk, the dairy-tolerant group had a unique response with lower lysine levels after drinking a2 Milk™, indicating that overall milk protein digestion is mostly unaffected by dairy intolerances.

Article Abstract

Background/objectives: Self-reported digestive intolerance to dairy foods is common. As dairy can be an important source of dietary protein, this study aimed to identify whether milk protein digestion is compromised in individuals with digestive intolerance.

Subjects/methods: Adult women (n = 40) were enroled in this double-blinded, randomised cross-over trial, with digestive symptoms characterised using a lactose challenge and self-reported digestive symptom questionnaire. Participants were classified as either lactose intolerant (LI, n = 10), non-lactose dairy intolerant (NLDI, n = 20) or dairy tolerant (DT, n = 10). In a randomised sequence, participants consumed three different kinds of milk (750 ml); conventional milk (CON), a2 Milk™ (A2M), and lactose-free conventional milk (LF-CON). Circulatory plasma amino acid (AA) concentrations were measured at baseline and every 30 min until 3 h post-ingestion.

Results: In all participants across all milk types, plasma AA concentrations (AUC) increased after milk ingestion with no significant differences in responses observed between milk types or participants (P > 0.05), with the exception of the suppressed lysine response in the DT group following A2M ingestion, relative to the other two groups and milk types (P < 0.05).

Conclusion: Milk protein digestion, as determined by circulatory AAs, is largely unaffected by dairy- and lactose- intolerances.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550627PMC
http://dx.doi.org/10.1038/s41430-022-01119-0DOI Listing

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