Background/objectives: Self-reported digestive intolerance to dairy foods is common. As dairy can be an important source of dietary protein, this study aimed to identify whether milk protein digestion is compromised in individuals with digestive intolerance.
Subjects/methods: Adult women (n = 40) were enroled in this double-blinded, randomised cross-over trial, with digestive symptoms characterised using a lactose challenge and self-reported digestive symptom questionnaire. Participants were classified as either lactose intolerant (LI, n = 10), non-lactose dairy intolerant (NLDI, n = 20) or dairy tolerant (DT, n = 10). In a randomised sequence, participants consumed three different kinds of milk (750 ml); conventional milk (CON), a2 Milk™ (A2M), and lactose-free conventional milk (LF-CON). Circulatory plasma amino acid (AA) concentrations were measured at baseline and every 30 min until 3 h post-ingestion.
Results: In all participants across all milk types, plasma AA concentrations (AUC) increased after milk ingestion with no significant differences in responses observed between milk types or participants (P > 0.05), with the exception of the suppressed lysine response in the DT group following A2M ingestion, relative to the other two groups and milk types (P < 0.05).
Conclusion: Milk protein digestion, as determined by circulatory AAs, is largely unaffected by dairy- and lactose- intolerances.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550627 | PMC |
http://dx.doi.org/10.1038/s41430-022-01119-0 | DOI Listing |
Allergol Immunopathol (Madr)
January 2025
Department of Pediatric Allergy and Immunology, Cemil Tascioglu City Hospital, University of Health Sciences, Istanbul, Turkey.
Background: Food protein-induced allergic proctocolitis is a nonimmunoglobulin E-mediated, self-limited food allergy of the rectum and the colon. Cow's milk protein is the most common allergen responsible for the disease.
Objective: This study aimed to investigate the roles of different types of formulas in building early tolerance to food protein-induced allergic proctocolitis in infants.
MCN Am J Matern Child Nurs
January 2025
Introduction: Lactation support services can improve exclusive breastfeeding rates among infants in the neonatal intensive care unit (NICU). There are limited data on how many NICUs offer these services.
Objective: To assess prevalence and type of lactation services provided in level III Canadian NICUs.
Food Res Int
January 2025
State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, Jiangxi 330047, China; Inner Mongolia Yili Industrial Group Co., Ltd, Hohhot, China. Electronic address:
Biomimetic membrane was investigated as model systems to mimic the structure of milk fat globule membrane (MFGM) and to study the effects of thermal processing-induced changes in MFGM fractions on membrane morphology and physical properties. Molecular docking was utilized to screen xanthine oxidase (XO) as the MFGM protein most likely to bind to phospholipid molecules on MFGM. Fluorescence spectroscopy verified that XO formed stable complexes with DOPE, DPPC, and PS 18:0-18:1, with the strongest binding to DOPE.
View Article and Find Full Text PDFFood Res Int
January 2025
VTT Technical Research Centre of Finland, Tekniikantie 21, 02044 VTT Espoo, Finland. Electronic address:
Oleaginous yeasts offer a promising sustainable alternative for producing edible lipids, potentially replacing animal and unsustainable plant fats and oils. In this study, we screened 11 oleaginous yeast species for their lipid profiles and identified Apiotrichum brassicae as the most promising candidate due to its versatility across different growth media. A.
View Article and Find Full Text PDFDrug Deliv Transl Res
January 2025
Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, Uttar Pradesh, India.
Cancer, particularly skin cancer, is a major cause of mortality worldwide, with melanoma being one of the most aggressive and challenging to treat types. Current therapeutic options, such as dacarbazine (DTIC), have limitations due to dose-related toxicities like liver toxicity. Therefore, there is a need for new and effective treatments for melanoma.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!