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Evaluation of the integration of retrieval-augmented generation in large language model for breast cancer nursing care responses.
Sci Rep
December 2024
College of Nursing, Binzhou Medical University, Yantai, Shandong Province, China.
Breast cancer is one of the most common malignant tumors in women worldwide. Although large language models (LLMs) can provide breast cancer nursing care consultation, inherent hallucinations can lead to inaccurate responses. Retrieval-augmented generation (RAG) technology can improve LLM performance, offering a new approach for clinical applications.
View Article and Find Full Text PDFOncological and Clinical Impacts of Routine Splenic Flexure Mobilization in Anterior Resection.
Cureus
November 2024
Colorectal Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Background Splenic flexure mobilization (SFM) is widely regarded as one of the most challenging steps in laparoscopic and robotic colorectal surgery, sparking ongoing debate. Some surgeons routinely advocate for SFM, citing its role in achieving greater left colonic reach, which facilitates a safe, tension-free, and well-vascularized anastomosis while adhering to oncological principles. Conversely, others argue that SFM does not consistently ensure these benefits and may increase the risk of complications, including splenic, bowel, or vascular injuries, as well as unnecessarily prolonging the procedure.
View Article and Find Full Text PDFEpidermal spongiotic Langerhans cell collections, but not eosinophils, are a clue to the diagnosis of allergic contact dermatitis: A series of 170 clinically- and patch test-confirmed cases.
J Am Acad Dermatol
December 2024
Department of Dermatology, University of California Davis School of Medicine, Sacramento, CA; Department of Pathology and Laboratory Medicine, University of California Davis School of Medicine, Sacramento, CA. Electronic address:
Background: Allergic contact dermatitis cannot be reliably differentiated from other forms of spongiotic/eczematous dermatitis by histology alone. Textbooks and recent studies have variably supported the specificity of dermal eosinophils, eosinophilic spongiosis, and Langerhans cell collections, among other features.
Objective: To assess which histopathologic features favor a diagnosis of allergic contact dermatitis.
Respiratory Syncytial Virus Disease Burden and Nirsevimab Effectiveness in Young Children From 2023-2024.
JAMA Pediatr
December 2024
Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Importance: During the 2023-2024 respiratory syncytial virus (RSV) season in the United States, 2 new RSV prevention products were recommended to protect infants in their first RSV season: nirsevimab and Pfizer's maternal RSV vaccine. Postlicensure studies are needed to assess prevention product impact and effectiveness.
Objective: To compare the epidemiology and disease burden of medically attended RSV-associated acute respiratory illness (ARI) among children younger than 5 years during the 2023-2024 RSV season with 3 prepandemic RSV seasons (2017-2020), estimate nirsevimab effectiveness against medically attended RSV-associated ARI, and compare nirsevimab binding site mutations among circulating RSV in infants with and without nirsevimab receipt.
Hospital Quality and Racial Differences in Outcomes After Genitourinary Cancer Surgery.
Cancer Med
December 2024
Department of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Article Synopsis
- - The study examines how hospital quality affects racial disparities in surgical outcomes for prostate, kidney, and bladder cancer among Black and White patients, using national Medicare data from 2017 to 2020.
- - Results showed that as hospital quality improved, the gap in successful surgical outcomes between Black and White patients decreased, with a noted 5.7% reduction in disparities for every 0.1 increase in hospital quality.
- - Additionally, Black patients were less likely to receive treatment at top-quality hospitals compared to their White counterparts (45.2% vs. 49.5%).
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