Objective: To assess whether there are differences in first-trimester fetal hepatic artery flows depending on pregnancy outcomes.
Methods: The prospective study conducted in 2012-2020 included 1841 fetuses from singleton pregnancies assessed during the routine first-trimester ultrasound examination (between 11- and 14-weeks' gestation). Also, each fetus was examined to determine their hepatic artery flows by measuring the artery's pulsatility index (HA-PI) and peak systolic velocity (HA-PSV).
Results: The fetuses that were classified as belonging to the adverse pregnancy outcome group (those with karyotype abnormalities and congenital heart defects) were characterized by a significantly lower HA-PI and higher HA-PSV compared to normal outcome fetuses.
Conclusion: Hepatic artery flow assessment proved to be a very useful tool in predicting adverse pregnancy outcomes, in particular karyotype abnormalities and congenital heart defects.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026841 | PMC |
| http://dx.doi.org/10.3390/jcm11082095 | DOI Listing |
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