Chemotherapy-Induced Liver Injury in Patients with Colorectal Liver Metastases: Findings from MR Imaging.

Diagnostics (Basel)

Department of Diagnostic, Interventional Radiology and Nuclear Medicine, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy.

Published: March 2022

AI Article Synopsis

  • Chemotherapy can often harm the liver, which is important for doctors to recognize to avoid misdiagnosing liver metastases.
  • MRI imaging serves as a valuable tool to identify changes in the liver that could lead to false negatives in detecting tumor responses after chemotherapy.
  • This review aims to outline MRI characteristics of liver damage from chemotherapy to improve diagnosis and appropriate treatment planning.

Article Abstract

Chemotherapy-induced liver injury has been found to be quite common in cancer patients undergoing chemotherapy. Being aware of chemotherapy-induced hepatotoxicity is important for avoiding errors in detecting liver metastases and for defining the most appropriate clinical management strategy. MRI imaging has proven to be a useful troubleshooting tool that helps overcome false negatives in tumor response imaging after chemotherapy due to liver parenchyma changes. The purpose of this review is, therefore, to describe the characteristics of magnetic resonance imaging of the broad spectrum of liver damage induced by systemic chemotherapeutic agents in order to avoid misdiagnoses of liver metastases and disease progression and to define the most appropriate clinical management strategy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029929PMC
http://dx.doi.org/10.3390/diagnostics12040867DOI Listing

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