AI Article Synopsis
- Lyme disease is caused by a bacterial infection from an infected tick bite, and initial treatment involves antibiotics; delayed treatment can lead to fatigue and issues with the nervous, cardiovascular, and joint systems.
- Damage in these areas is primarily due to the body's extreme inflammatory response, which creates a vicious cycle of mitochondrial dysfunction and oxidative stress.
- The article explores the potential use of coenzyme Q10 (CoQ10) as a supplement to help improve mitochondrial function and reduce inflammation and oxidative stress in Lyme disease patients.
Article Abstract
Lyme disease results from a bacterial infection following a bite from an infected tick. Patients are initially treated with antibiotics; however, in cases where antibiotic treatment is delayed, or when patients do not respond to antibiotic treatment, fatigue may develop alongside problems affecting the nervous system, cardiovascular system, and joints. It is thought that most of the damage to these tissues results from the excessive inflammatory response of the host, involving a self-reinforcing cycle of mitochondrial dysfunction, oxidative stress and inflammation. In this article, we review the potential role of supplementary coenzyme Q10 (CoQ10) in mediating the pathogenic mechanism underlying Lyme disease, on the basis of its role in mitochondrial function, as well as its anti-inflammatory and antioxidant actions.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027459 | PMC |
| http://dx.doi.org/10.3390/antiox11040667 | DOI Listing |
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